{"id":5,"date":"2016-05-10T18:18:00","date_gmt":"2016-05-10T18:18:00","guid":{"rendered":"http:\/\/depts.washington.edu\/tlcart\/?page_id=5"},"modified":"2018-10-09T17:27:06","modified_gmt":"2018-10-09T17:27:06","slug":"home","status":"publish","type":"page","link":"https:\/\/depts.washington.edu\/tlcart\/home\/","title":{"rendered":"Innovations in Targeted &#038; Long Acting Therapy to clear HIV"},"content":{"rendered":"<h3>Targeted Long Acting Therapy intended to clear the HIV virus.<\/h3>\n<div id=\"metaslider-id-46\" style=\"max-width: 850px;\" class=\"ml-slider-3-110-0 metaslider metaslider-flex metaslider-46 ml-slider has-dots-nav ms-theme-default\" role=\"region\" aria-label=\"Homepage\" data-height=\"425\" data-width=\"850\">\n<div id=\"metaslider_container_46\">\n<div id=\"metaslider_46\">\n<ul class='slides'>\n<li style=\"display: block; width: 100%;\" class=\"slide-98 ms-image \" aria-roledescription=\"slide\" data-date=\"2016-05-27 23:28:09\" data-filename=\"Ho-Collier-TLCART-Group-Photo-2-850x425.jpg\" data-slide-type=\"image\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/depts.washington.edu\/tlcart\/wp-content\/uploads\/2016\/05\/Ho-Collier-TLCART-Group-Photo-2-850x425.jpg\" height=\"425\" width=\"850\" alt=\"\" class=\"slider-46 slide-98 msDefaultImage\" \/><\/li>\n<li style=\"display: none; width: 100%;\" class=\"slide-24 ms-image \" aria-roledescription=\"slide\" data-date=\"2016-05-10 18:49:39\" data-filename=\"Rodney_Ho_Lab_IMG_0661_WEB2-1024x683-850x425.jpg\" data-slide-type=\"image\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/depts.washington.edu\/tlcart\/wp-content\/uploads\/2016\/05\/Rodney_Ho_Lab_IMG_0661_WEB2-1024x683-850x425.jpg\" height=\"425\" width=\"850\" alt=\"\" class=\"slider-46 slide-24 msDefaultImage\" \/><\/li>\n<li style=\"display: none; width: 100%;\" class=\"slide-970 ms-image \" aria-roledescription=\"slide\" data-date=\"2016-11-10 00:47:58\" data-filename=\"TLC-ART-Group-Photo-2-1-850x425.jpg\" data-slide-type=\"image\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/depts.washington.edu\/tlcart\/wp-content\/uploads\/TLC-ART-Group-Photo-2-1-850x425.jpg\" height=\"425\" width=\"850\" alt=\"\" class=\"slider-46 slide-970 msDefaultImage\" \/><\/li>\n<li style=\"display: none; width: 100%;\" class=\"slide-3116 ms-image \" aria-roledescription=\"slide\" data-date=\"2025-07-13 20:13:40\" data-filename=\"IMG_8727-850x425.jpeg\" data-slide-type=\"image\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/depts.washington.edu\/tlcart\/wp-content\/uploads\/IMG_8727-850x425.jpeg\" height=\"425\" width=\"850\" alt=\"\" class=\"slider-46 slide-3116 msDefaultImage\" title=\"IMG_8727\" \/>\n<div class=\"caption-wrap\">\n<div class=\"caption\">\n<div>CROI 2025<\/div>\n<\/div>\n<\/div>\n<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/div>\n<p>We are the\u00a0<strong>T<\/strong>argeted\u00a0<strong>L<\/strong>ong-acting\u00a0<strong>C<\/strong>ombination\u00a0<strong>A<\/strong>nti-<strong>R<\/strong>etroviral <strong>T<\/strong>herapy (TLC-ART) program, located within the Department of Pharmaceutics at the University of Washington.\u00a0 We are\u00a0scientists and physicians working toward developing a long acting and\u00a0effective treatment to improve patient compliance and\u00a0therapeutic outcomes in the treatment of HIV. Our hope is to maximally suppress HIV and potentially contribute to a cure for AIDS.<\/p>\n<p>In the past, HIV treatments involved a complicated regimen of certain drugs taken at specific times. Our goal is to launch a 3-drug combination called TLC-ART.\u00a0 TLC-ART, unlike other HIV treatments, TLC-ART will only need to be taken once a month.<\/p>\n<p><span style=\"margin: 0px; color: #3d3d3d; font-family: 'Calibri',sans-serif; font-size: 14pt;\">Our\u00a0researchers were the first to\u00a0document\u00a0pharmacological drug deficiencies with HIV oral treatment. This\u00a0has been\u00a0linked to residual HIV in tissues. The TLC-ART program, with its 11 projects, intends to overcome pharmacological drug deficiency by developing a novel formulation of a combination of antiretroviral agents. TLC-ART is a publicly funded, National Institutes of Health (<\/span><span style=\"margin: 0px; color: #0088dd; font-family: 'Calibri',sans-serif; font-size: 14pt;\"><a href=\"https:\/\/projectreporter.nih.gov\/project_info_description.cfm?aid=8970537&amp;icde=29062145&amp;ddparam=&amp;ddvalue=&amp;ddsub=&amp;cr=1&amp;csb=default&amp;cs=ASC\" target=\"_blank\" rel=\"noopener\">NIH)<\/a><\/span><span style=\"margin: 0px; color: #3d3d3d; font-family: 'Calibri',sans-serif; font-size: 14pt;\">\u00a0supported program with contributions from multiple institutions.<\/span><\/p>\n<p><img decoding=\"async\" style=\"max-width: 300px; float: right;\" src=\"\/tlcart\/wp-content\/uploads\/tlcart-1.jpg\" usemap=\"#Map\" \/><\/p>\n<map name=\"Map\">\n<area alt=\"School of Pharmacy\" coords=\"148,45,42\" shape=\"circle\" href=\"https:\/\/sop.washington.edu\/\" target=\"_blank\" rel=\"noopener noreferrer\" \/>\n<area alt=\"School of Medicine\" coords=\"64,84,40\" shape=\"circle\" href=\"http:\/\/www.uwmedicine.org\/\" target=\"_blank\" rel=\"noopener noreferrer\" \/>\n<area alt=\"Institute for Translational Health Sciences\" coords=\"44,175,40\" shape=\"circle\" href=\"https:\/\/www.iths.org\/\" target=\"_blank\" rel=\"noopener noreferrer\" \/>\n<area alt=\"Seattle Children's\" coords=\"101,248,41\" shape=\"circle\" href=\"https:\/\/www.seattlechildrens.org\/\" target=\"_blank\" rel=\"noopener noreferrer\" \/>\n<area alt=\"Harborview\" coords=\"197,247,41\" shape=\"circle\" href=\"http:\/\/www.uwmedicine.org\/harborview\" target=\"_blank\" rel=\"noopener noreferrer\" \/>\n<area alt=\"Fred Hutch\" coords=\"256,173,42\" shape=\"circle\" href=\"http:\/\/www.fredhutch.org\/\" target=\"_blank\" rel=\"noopener noreferrer\" \/>\n<area alt=\"Center for AIDS Research\" coords=\"233,84,39\" shape=\"circle\" href=\"http:\/\/depts.washington.edu\/cfar\/\" target=\"_blank\" rel=\"noopener noreferrer\" \/> <\/map>\n<p>&nbsp;<\/p>\n<p>We welcome your <a href=\"https:\/\/depts.washington.edu\/tlcart\/contact\/\" target=\"_blank\" rel=\"noopener noreferrer\">input<\/a>, research support, <a href=\"https:\/\/depts.washington.edu\/tlcart\/contact\/\" target=\"_blank\" rel=\"noopener noreferrer\">participation<\/a> and donations by either <a href=\"https:\/\/www.washington.edu\/giving\/make-a-gift\/?page=make&amp;code=HOPHAR\" target=\"_blank\" rel=\"noopener\">making a gift<\/a> or donating directly to our <a href=\"https:\/\/sop.washington.edu\/alumni-donors\/give-to-the-school\/faculty\/\" target=\"_blank\" rel=\"noopener noreferrer\">faculty<\/a> or <a href=\"https:\/\/sop.washington.edu\/alumni-donors\/give-to-the-school\/students\/\" target=\"_blank\" rel=\"noopener noreferrer\">students<\/a>.<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Targeted Long Acting Therapy intended to clear the HIV virus. We are the\u00a0Targeted\u00a0Long-acting\u00a0Combination\u00a0Anti-Retroviral Therapy (TLC-ART) program, located within the Department of Pharmaceutics at the University of Washington.\u00a0 We are\u00a0scientists and physicians working toward developing a long acting and\u00a0effective treatment to improve patient compliance and\u00a0therapeutic outcomes in the treatment of HIV. Our hope is to maximally suppress HIV and potentially contribute to a cure for AIDS. In the past, HIV treatments involved a complicated regimen of certain drugs taken at specific&#8230;<\/p>\n<div><a class=\"more-link\" href=\"https:\/\/depts.washington.edu\/tlcart\/home\/\">Continue reading <span class=\"screen-reader-text\">Innovations in Targeted &#038; Long Acting Therapy to clear HIV<\/span><\/a><\/div>\n","protected":false},"author":2,"featured_media":970,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-5","page","type-page","status-publish","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/tlcart\/wp-json\/wp\/v2\/pages\/5","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/tlcart\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/depts.washington.edu\/tlcart\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/tlcart\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/tlcart\/wp-json\/wp\/v2\/comments?post=5"}],"version-history":[{"count":64,"href":"https:\/\/depts.washington.edu\/tlcart\/wp-json\/wp\/v2\/pages\/5\/revisions"}],"predecessor-version":[{"id":1730,"href":"https:\/\/depts.washington.edu\/tlcart\/wp-json\/wp\/v2\/pages\/5\/revisions\/1730"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/tlcart\/wp-json\/wp\/v2\/media\/970"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/tlcart\/wp-json\/wp\/v2\/media?parent=5"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}