Principal Investigator
Email: slarnold@uw.edu
Dr. Samuel Arnold joined the Department of Pharmaceutics at the University of Washington as an Assistant Professor in 2023, and he is the director of the Pharmacokinetics and Modeling Lab which supports the development and application of LC-MS assays for small molecules and proteins. In addition, Dr. Arnold’s lab works on the development of in vitro and in vivo models for major etiological agents of diarrheal disease (e.g., Cryptosporidium and Shigella). While there has been a substantial reduction in diarrhea associated mortality over the past decade, diarrheal diseases continue to be a major global health concern (second leading cause of death in children < 5 years old). Models of in vitro and in vivo infection developed by the Arnold lab support their studies to identify pharmacokinetic/pharmacodynamic (PK/PD) relationships for therapeutic treatment of enteric infections.