{"id":185,"date":"2015-03-20T00:27:33","date_gmt":"2015-03-20T00:27:33","guid":{"rendered":"http:\/\/depts.washington.edu\/uwviro\/wordpress\/?page_id=185"},"modified":"2024-06-24T17:07:58","modified_gmt":"2024-06-24T17:07:58","slug":"hepatitis-serologies","status":"publish","type":"page","link":"https:\/\/depts.washington.edu\/uwviro\/hepatitis-serologies\/","title":{"rendered":"Viral Serologies"},"content":{"rendered":"\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/testguide.labmed.uw.edu\/public\/\">SEARCH THE ONLINE LABORATORY TEST CATALOG<\/a><\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group accordion is-layout-flow wp-block-group-is-layout-flow\">\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button accordion-expand\"><a class=\"wp-block-button__link wp-element-button\">Expand All<\/a><\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group accordion-panel is-layout-flow wp-block-group-is-layout-flow\">\n<h4 class=\"wp-block-heading panel-heading\">Cytomegalovirus (CMV)<\/h4>\n\n\n\n<div class=\"wp-block-group panel-content is-layout-flow wp-block-group-is-layout-flow\">\n<p>Cytomegalovirus (CMV) antibody screen is run 3 times daily on Monday through Friday. The antibody screen is a qualitative detection of CMV IgG class antibodies in human sera by the FDA approved Zeus ELISA (enzyme-linked immunosorbent assay) test system.<\/p>\n\n\n\n<p>Search&nbsp;<strong><a href=\"https:\/\/testguide.labmed.uw.edu\/public\/view\/CMVS\" target=\"_blank\" rel=\"noreferrer noopener\">CMVS<\/a><\/strong>&nbsp;code in the online Laboratory Test Catalog.<\/p>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group accordion-panel is-layout-flow wp-block-group-is-layout-flow\">\n<h4 class=\"wp-block-heading panel-heading\">Epstein Barr Virus (EBV)<\/h4>\n\n\n\n<div class=\"wp-block-group panel-content is-layout-flow wp-block-group-is-layout-flow\">\n<p>Epstein-Barr Virus virus detection is run 3 times daily on Monday through Friday and is the qualitative detection of Epstein-Barr virus (EBV) Viral Capsid Antigen (VCA) IgG, VCA IgM, and Nuclear Antigen (EBNA) IgG class antibodies in human sera by the FDA approved Zeus ELISA (enzyme-linked immunosorbent assay) test system. Results are reported as either Reactive, Equivocal or NON-reactive.<\/p>\n\n\n\n<p>Search&nbsp;<a href=\"https:\/\/testguide.labmed.uw.edu\/public\/view\/EBVEIA\" target=\"_blank\" rel=\"noreferrer noopener\">EBVEIA<\/a>&nbsp;code in the online Laboratory Test Catalog.<\/p>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group accordion-panel is-layout-flow wp-block-group-is-layout-flow\">\n<h4 class=\"wp-block-heading panel-heading\">Hepatitis A<\/h4>\n\n\n\n<div class=\"wp-block-group panel-content is-layout-flow wp-block-group-is-layout-flow\">\n<p>shedding occurs in the weeks before clinical symptoms appear. Hepatitis A antibody testing is performed 2 times daily, Monday through Friday; IgM antibody tests are performed on all reactive specimens. Hepatitis A IgM indicates acute infection. All positive Hepatitis A IgM results are called to the requesting physician or laboratory and the local King County Dept. of Health. The physician must also report acute Hepatitis A infections to the local County Department of Public Health (in King County, telephone the Communicable Disease Department at (206) 296-4774). For vaccine recipients a Hepatitis A vaccine screen can be ordered. This assay does not include IgG\/IgM differentiation if positive.<\/p>\n\n\n\n<p>Search<a href=\"https:\/\/testguide.labmed.uw.edu\/public\/view\/HAVIGG\" target=\"_blank\" rel=\"noreferrer noopener\"><strong>&nbsp;HAVIGG&nbsp;<\/strong><\/a>or<a href=\"https:\/\/testguide.labmed.uw.edu\/public\/view\/HAVIGM\" target=\"_blank\" rel=\"noreferrer noopener\"><strong>&nbsp;HAVIGM&nbsp;<\/strong><\/a>code in the online Laboratory Test Catalog.<\/p>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group accordion-panel is-layout-flow wp-block-group-is-layout-flow\">\n<h4 class=\"wp-block-heading panel-heading\">Hepatitis B<\/h4>\n\n\n\n<div class=\"wp-block-group panel-content is-layout-flow wp-block-group-is-layout-flow\">\n<p>Hepatitis B is transmitted through blood or secretions of infected patients. Infectivity of a patient is determined by enzyme immunoassay for Hepatitis B surface antigen (HBsAg), which is run Monday through Friday. Reports of reactive HBsAg are called to the ordering physician or laboratory and are automatically run for Hepatitis B viral DNA by PCR. Patients with needle sticks and other parenteral exposures need to receive Hepatitis B Immune Globulin within 72 hours of exposure. The routine HBsAg run can accommodate most specimens generated by accidental parenteral exposure. The physician must also report acute Hepatitis B infections to the local County Department of Public Health (in King County, telephone the Communicable Disease Department at (206) 296-4774).<\/p>\n\n\n\n<p>Note: Positive HBsAg will reflex to a Hepatitis B DNA by PCR at an additional charge.<\/p>\n\n\n\n<p>Search<a href=\"https:\/\/testguide.labmed.uw.edu\/public\/view\/HBSAG\" target=\"_blank\" rel=\"noreferrer noopener\"><strong>&nbsp;HBSAG&nbsp;<\/strong><\/a>or&nbsp;<a href=\"https:\/\/testguide.labmed.uw.edu\/public\/view\/HBSAGX\" target=\"_blank\" rel=\"noreferrer noopener\"><strong>HBSAGX<\/strong><\/a>&nbsp;code in the online Laboratory Test Catalog.<\/p>\n\n\n\n<p><strong>See&nbsp;<a href=\"https:\/\/depts.washington.edu\/labweb\/Divisions\/Viro\/images\/page33b.jpg\" target=\"_blank\" rel=\"noreferrer noopener\">Hepatitis B Chart 1<\/a>,&nbsp;<a href=\"https:\/\/depts.washington.edu\/labweb\/Divisions\/Viro\/images\/page33c.jpg\" target=\"_blank\" rel=\"noreferrer noopener\">Chart 2<\/a>, and&nbsp;<a href=\"https:\/\/depts.washington.edu\/labweb\/Divisions\/Viro\/images\/page33d.jpg\" target=\"_blank\" rel=\"noreferrer noopener\">Chart 3<\/a><\/strong><\/p>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group accordion-panel is-layout-flow wp-block-group-is-layout-flow\">\n<h4 class=\"wp-block-heading panel-heading\">Hepatitis B Surface Antibody &amp; Hepatitis B Core Antibody<\/h4>\n\n\n\n<div class=\"wp-block-group panel-content is-layout-flow wp-block-group-is-layout-flow\">\n<p>Hepatitis B surface antibody (anti-HBs) and Hepatitis B core antibody (anti-HBc) assays are useful for identifying persons susceptible to Hepatitis B infection (i.e. needle stick exposures), for documenting persons with past infection with Hepatitis B virus, for vaccine screening, and for determining response to vaccination. The Hepatitis B surface antibody result is reported international units (I.U.) of Hepatitis B surface antibody. Values above a test standard containing 10 I.U. of Hepatitis B surface antibody are considered protective levels. Vaccination\/re-vaccination is warranted with values below this level. Anti-HBs assays and anti-HBc assays are performed daily Monday through Friday.<\/p>\n\n\n\n<p>Search<a href=\"https:\/\/testguide.labmed.uw.edu\/public\/view\/HBSS\" target=\"_blank\" rel=\"noreferrer noopener\"><strong>&nbsp;HBSS&nbsp;<\/strong><\/a>code in the online Laboratory Test Catalog for information on Hepatitis B Surface Antibody (HBsAb).<\/p>\n\n\n\n<p>Search<a href=\"https:\/\/testguide.labmed.uw.edu\/public\/view\/HBCA\" target=\"_blank\" rel=\"noreferrer noopener\"><strong>&nbsp;HBCA&nbsp;<\/strong><\/a>code in the online Laboratory Test Catalog for information on Hepatitis B Core Antibody (HBcAb).<\/p>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group accordion-panel is-layout-flow wp-block-group-is-layout-flow\">\n<h4 class=\"wp-block-heading panel-heading\">Hepatitis B Core IgM Antibodies<\/h4>\n\n\n\n<div class=\"wp-block-group panel-content is-layout-flow wp-block-group-is-layout-flow\">\n<p>Presence of Hepatitis B core IgM antibodies helps to distinguish chronic carriers of HBsAg from acute cases of Hepatitis B. Persons with recent exposure to Hepatitis B will be reactive for core IgM, while chronic carriers of HBsAg will not. This test is sent out to a Reference lab.<\/p>\n\n\n\n<p>Search&nbsp;<a href=\"https:\/\/testguide.labmed.uw.edu\/public\/view\/RHBCAM\" target=\"_blank\" rel=\"noreferrer noopener\"><strong>RHBCM<\/strong><\/a>&nbsp;code in the online Laboratory Test Catalog for information on Hepatitis B Core IgM Antibody.<\/p>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group accordion-panel is-layout-flow wp-block-group-is-layout-flow\">\n<h4 class=\"wp-block-heading panel-heading\">Hepatitis A &amp; B Battery<\/h4>\n\n\n\n<div class=\"wp-block-group panel-content is-layout-flow wp-block-group-is-layout-flow\">\n<p>Hepatitis A &amp; B Battery consists of the HBsAg, anti-HBs, anti-HBc and anti-Hep A tests. The laboratory requires 3-5 mL clotted blood or 1-2 mL of sera for the full battery.<\/p>\n\n\n\n<p>Note: A positive HBsAg reflexes to a Hepatitis B by PCR, quant. at an additional charge.<\/p>\n\n\n\n<p>Search<a href=\"https:\/\/testguide.labmed.uw.edu\/public\/view\/HBB\" target=\"_blank\" rel=\"noreferrer noopener\"><strong>&nbsp;HBB&nbsp;<\/strong><\/a>code in the online Laboratory Test Catalog for information on Hepatitis A &amp; B Battery.<\/p>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group accordion-panel is-layout-flow wp-block-group-is-layout-flow\">\n<h4 class=\"wp-block-heading panel-heading\">Hepatitis B &#8216;e&#8217; Antigen and Antibody<\/h4>\n\n\n\n<div class=\"wp-block-group panel-content is-layout-flow wp-block-group-is-layout-flow\">\n<p>The Qualitative detection of Hepatitis B virus \u201ce\u201d antigen (HBeAg) and Hepatitis B virus \u201ce\u201d antibody (HBeAb) in human sera by the FDA approved DiaSorin Diagnostic HBe enzyme immunoassay (EIA).<\/p>\n\n\n\n<p>The presence of HBeAg in serum is associated with presence of Dane particles and Hepatitis B virus (HBV) DNA polymerase enzyme. These markers suggest active HBV replication. Hepatitis B Surface antigen (HBsAg) positive and HBeAg positive persons are much more likely to transmit infections to others. The development of anti-HBe during acute Hepatitis B infection is a marker of resolution of illness.<\/p>\n\n\n\n<p>Search&nbsp;<a href=\"https:\/\/testguide.labmed.uw.edu\/public\/view\/HBE\" target=\"_blank\" rel=\"noreferrer noopener\">HBE<\/a>&nbsp;code in the online Laboratory Test Catalog.<\/p>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group accordion-panel is-layout-flow wp-block-group-is-layout-flow\">\n<h4 class=\"wp-block-heading panel-heading\">Hepatitis C Virus (HCV)<\/h4>\n\n\n\n<div class=\"wp-block-group panel-content is-layout-flow wp-block-group-is-layout-flow\">\n<p>Hepatitis C is the leading cause of post transfusion hepatitis and of \u201cnon-A, non-B\u201d hepatitis. It may be acquired by blood products or by non-parenteral routes. Most HCV infections are sub-clinical, and chronic hepatitis is common. All positive Hepatitis C antibodies are confirmed by PCR at an additional charge. Hepatitis C Antibody screens are run daily, Mon. \u2013 Sat.<\/p>\n\n\n\n<p>Search&nbsp;<a href=\"https:\/\/testguide.labmed.uw.edu\/public\/view\/HCAB\" target=\"_blank\" rel=\"noreferrer noopener\">HCAB<\/a>&nbsp;or&nbsp;<a href=\"https:\/\/testguide.labmed.uw.edu\/public\/view\/HCABX\" target=\"_blank\" rel=\"noreferrer noopener\">HCABX&nbsp;<\/a>code in the online Laboratory Test Catalog.<\/p>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Cytomegalovirus (CMV) Cytomegalovirus (CMV) antibody screen is run 3 times daily on Monday through Friday. The antibody screen is a qualitative detection of CMV IgG class antibodies in human sera by the FDA approved Zeus ELISA (enzyme-linked immunosorbent assay) test system. Search&nbsp;CMVS&nbsp;code in the online Laboratory Test Catalog. Epstein Barr Virus (EBV) Epstein-Barr Virus virus [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"open","ping_status":"open","template":"","meta":{"footnotes":""},"class_list":["post-185","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/uwviro\/wp-json\/wp\/v2\/pages\/185","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/uwviro\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/depts.washington.edu\/uwviro\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/uwviro\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/uwviro\/wp-json\/wp\/v2\/comments?post=185"}],"version-history":[{"count":39,"href":"https:\/\/depts.washington.edu\/uwviro\/wp-json\/wp\/v2\/pages\/185\/revisions"}],"predecessor-version":[{"id":2380,"href":"https:\/\/depts.washington.edu\/uwviro\/wp-json\/wp\/v2\/pages\/185\/revisions\/2380"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/uwviro\/wp-json\/wp\/v2\/media?parent=185"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}