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Vol. IV, No. 10 ~ EINet News Briefs ~ June 22, 2001


****A free service of the APEC Emerging Infections Network*****

The EINet listserv was created to foster discussion, networking, and collaboration in the area of emerging infectious diseases (EID's) among academicians, scientists, and policy makers in the Asia–Pacific region. We strongly encourage you to share their perspectives and experiences, as your participation directly contributes to the richness of the "electronic discussions" that occur. To respond to the listserv, use the reply function.


In this edition:

  1. Infectious disease information
  2. Updates
  3. Notices
  4. How to join the EINet listserv


1. OVERVIEW OF INFECTIOUS–DISEASE INFORMATION  
Below is a bi–monthly summary of Asia–Pacific emerging infectious diseases.

ASIA

MALAYSIA (KUALA LUMPUR) – DENGUE OUTBREAK
Two women died from brain hemorrhages caused by dengue fever in an outbreak in northern Malaysia that has infected 24 people. The outbreak occurred in Perlis state, near the Malaysia–Thai border, where villages are being fumigated in an attempt to contain the outbreak. The two women who died were sisters, 44 and 53 years of age. This outbreak is the second in Malaysia this year. The first occurred in February, when two people died and 242 others were infected in the central Malaysian state of Negeri Sembilan.

Dengue fever is common in tropical regions, and is spread by mosquitoes. It is characterized by headaches, rashes, cramps, and severe back and muscle pains. The infection can be fatal if treatment is delayed.
[ASSOCIATED PRESS 6/11/01]

CHINA (HONG KONG) – vCJD CASE CONFIRMED
A 34–year–old Chinese woman is believed to be suffering from variant Creutzfeldt –Jakob Disease (vCJD), the human counterpart to bovine spongiform encephalopathy (BSE), according to Britain’s National Creutzfeldt–Jakob Disease Surveillance Unit. The woman is currently being treated at the Prince of Wales Hospital in Hong Kong, but she spent considerable time in Britain. Dr. Donald Lyon, of the Prince of Wales Hospital, believes that the woman likely contracted the disease from eating contaminated beef in Britain, where she lived from 1985 to 1992, and from 1997 until earlier this year, when she returned to Hong Kong. This is the first time that vCJD has appeared in Asia.

vCJD was first detected in Britain in 1996, where over 100 cases have been reported. People are believed to contract the infection as a result of eating beef from cattle infected with BSE. Hong Kong has banned imports of British beef since 1996.
[YAHOO ASIA NEWS 6/9/01, http://asia.dailynews.yahoo.com; ASSOCIATED PRESS 6/14/01]

CHINA (HONG KONG) – CHOLERA CLUSTER
The Department of Health of the Hong Kong SAR has diagnosed and confirmed cholera infection in 6 individuals between mid–May and early June. A 61–year–old woman from Kwai Chung was the first to be diagnosed, and she indicated that she had not traveled outside Hong Kong during the incubation period. Vibrio cholerae 01 El Tor Inaba was isolated from each of the cases. The source of the infection is being investigated.
[PROMED 6/9/01, 6/11/01]


AMERICAS

PERU – YELLOW FEVER OUTBREAK
Eight cases of yellow fever have been confirmed in the Department of Loreto, in the Amazon Region of Peru. Two cases have died and an additional 12 are under investigation. The Pan American Health Organization (PAHO) has mobilized 400,000 doses of vaccine for a vaccination campaign.
[WHO Disease Outbreaks Reports; http://www.who.int/disease–outbreak–news]

CANADA (ONTARIO) – E. COLI EXTENDED SPECTRUM BETA LACTAMASE (ESBL) OUTBREAK
An outbreak of a drug–resistant strain of E. coli has spread among eight seniors’ homes throughout Greater Toronto, infecting at least 100 people in the Durham Region and undetermined numbers in the York Region and Scarborough. This strain of E. coli, thought to be extended spectrum beta lactamase (ESBL), is a variation of a common bacterium in the digestive tract that has developed resistance to antibiotics. The infection is spread through contact with feces of an infected person. According to the Associate Medical Officer of health for Durham Region, people with healthy immune systems can generally fight off the infection, but it can be extremely serious for frail and elderly individuals. Five elderly people have died from conditions that may have been exacerbated by the infection.

This outbreak began in July of 2000 when the infection was identified in several patients at a Durham hospital. The infection spread to seniors’ homes in Scarborough when infected seniors moved from Durham to Scarborough. The origin of the York Region cluster remains unknown. In many of the 100 Durham cases the bacteria has colonized in patients’ intestines without any symptoms. Hospital staff are closely monitoring patients who have tested positive and testing them every two to four weeks. Officials of the seniors’ facilities have been advised to exercise strict sanitary precautions when working with infected individuals. All other residents at the homes are being tested.
[TORONTO STAR, http://www.torontostar.com]

CANADA – TO BEGIN TESTING IMMIGRANTS FOR HIV
Canada will begin mandatory HIV testing of all immigrants and people seeking refugee status. According to the Immigration Minister, each case will be evaluated individually so that a positive test would not necessarily result in automatic exclusion from Canada. An important consideration in the decision would focus on the extent to which the individual’s illness would burden the nation’s health care system. Currently, immigrants
can be excluded from Canada for leprosy, mental handicaps, and other conditions, but they are not required to be tested for HIV. The Health Minister stated that the policy would put Canadian policies more in line with those of other Western countries. The Canadian Council for Refugees criticized the policy, claiming that it would result in increased stigmatization of immigrants.
[ASSOCIATED PRESS 6/13/01]

U.S. – TRANSMISSION OF DIARRHEAL INFECTIONS IN RECREATIONAL FACILITIES INCREASES
The CDC reports that the transmission of diarrheal infections as a result of swallowing fecal contaminated water while swimming in pools and other recreational areas increased during the 1990’s. Approximately 10,000 cases and 32 outbreaks of waterborne diarrhea were linked to pools, waterparks, spas, and other facilities in the U.S. from 1989 to 1998. This increase was attributed in large part to the fact that many people continue to swim while sick, presumably because most people do not consider diarrhea a serious illness. An epidemiologist from the CDC’s National Center for Infectious Diseases stated that one person with diarrhea could contaminate an entire swimming pool for several days.
The majority of the outbreaks associated with swimming pools were caused by Cryptosporidium, a parasite that is highly resistant to chlorine.

The CDC has issued recommendations to reduce the transmission of pool–related diarrhea, including enhanced awareness and education for both the public and pool operators as to the risks of fecal transmission in pools, creating bathroom breaks for kids, and separate filtration systems for “kiddie” pools. Most importantly, the CDC suggested that sick individuals should refrain from swimming while ill and until two weeks after the diarrhea has stopped, as Cryptosporidium can be excreted several weeks after diarrhea has ceased.
[MMWR 2001;50:406𤮊, http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5020a3.htm; PROMED 5/28/01]


2. UPDATES

SUMMARY – APEC 20th ISTWG SIDE MEETING ON EMERGING INFECTIOUS DISEASES
A summary of the side meeting on emerging infectious diseases that was held on April 24, 2001, at the 20th APEC Industrial Science and Technology Working Group (ISTWG) is now posted on the APEC Science and Technology website for registered users at http://www.apecst.org/site/index.cfm. Twenty–eight representatives from 10 APEC economies, including Canada, Hong Kong, China, Japan, Korea, Malaysia, Chinese Taipei, Thailand, United States, and Vietnam, met to discuss ongoing projects, new project proposals, and strategies for APEC to address HIV/AIDS and emerging infectious diseases. New project proposals that received endorsement included the Molecular Epidemiology of Dengue Viruses, Preventing Emerging Infections in the Asia Pacific: Creating a Network of Networks, Emerging Infections Outbreak Response Training, and The Impact of HIV/AIDS on the Business Sector in the Asia Pacific Region – Policy Forum on Developing a Regional Business Response.


3. NOTICES

PLEASE HELP!! NOMINATE ASIA PACIFIC–BASED DISEASE SURVEILLANCE NETWORKS!
APEC is committed to a network of networks strategy to enhance disease alert and surveillance activity in our region. PLEASE HELP! Nominate by July 15th any regional or national Asia Pacific–based networks for disease alert or surveillance that you have found helpful in your work. These include electronic networks other than EINet that you use to obtain disease alert and surveillance information, such as those related to HIV/AIDS or microbial resistance, etc. Please send this information, including the names of principal contacts, to apecein@u.washington.edu.
Your help is greatly appreciated.

CALL FOR INFORMATION ON DRUG USE AND HIV VULNERABILITY IN ASIA
The Centre for Harm Reduction (CHR) and the Asian Harm Reduction Network (AHRN) are undertaking a Rapid Situation Assessment of drug use and HIV/AIDS vulnerability in Asia. The project is collecting all available information on illicit drug use and on HIV infection among illicit drug users in 22 Asian countries, from Mongolia to Iran, and is to be completed within the next 12 weeks.

The CHR is requesting any material from APEC–EINet subscribers relating to aspects of the twin themes of illicit drug use and HIV infection in the Asian region. This may include published or unpublished material, reports, articles, books, websites, or videos, as well as the names of organizations active in these areas.

The first Regional Situation Assessment, entitled The Hidden Epidemic, was conducted in 1997 and was influential in raising the profile of HIV epidemics among injecting drug users and their families in the Asian region. This report is available at the AHRN website at http://www.ahrn.net, under publications. The new assessment will monitor changes that have occurred since then, and examine countries previously not investigated.

Please direct all information and questions to Gary Reid at the Centre for Harm Reduction in Australia at reid@burnet.edu.au.

OVER 10 MILLION YOUTH INFECTED WITH HIV
The United Nations Children’s Fund (UNICEF) announced that 10.3 million youth aged 15 to 24 are living with HIV/AIDS worldwide, with the majority in sub–Saharan Africa. According to their report, many sexually active youth exhibit low levels of HIV knowledge, even for those in countries with high infection rates. For example in Mozambique, almost 74% of girls and 62% of boys aged 15 to 19 are unaware of prevention measures. Likewise, an estimated 16 million girls aged 15 to 19 in sub–Saharan Africa do not realize that individuals who appear healthy may be infected with HIV. UNICEF proposes enhancing “youth friendly” health services to provide youth access to HIV testing, counseling, and information. The UN General Assembly will be hosting a special session on HIV/AIDS on June 25㪳.
[UN WIRE 6/13/01, http://www.unfoundation.org/unwire/2001/06/13/index.asp#15246]

WHO, FAO, OIE–SPONSORED CONFERENCE ON BSE, JUNE 11㪧
The UN Food and Agriculture Organization (FAO), the World Health Organization (WHO), and the World Organization for Animal Health (OIE) sponsored a four–day conference in Paris for international veterinarians, food safety experts, and health officials to develop methods of combating the spread of bovine spongiform encephalopathy (BSE). The organizations, along with over 150 conference attendees, called on governments worldwide to ban the feeding of meat and bone meal to ruminants and increase surveillance of the disease. They also issued 13 recommendations to prevent BSE, such as urging countries to assess trade and possible risk factors for potential exposure, highlighting the need for more specific guidance for conducting risk assessments, and emphasizing that risk management must be based on science, among others. To view the recommendations, visit the following URL: http://www.who.int/inf–pr�/en/pr2001㪴.html.
[WHO PRESS RELEASE 6/14/01]


4. JOIN THE E–LIST AND RECEIVE EINet NEWS BRIEFS REGULARLY
The APEC EINet listserv was established to enhance collaboration among academicians and public health professionals in the area of emerging infections surveillance and control. Subscribers are encouraged to share their material with colleagues in the Asia–Pacific Rim. To subscribe (or unsubscribe), please contactmailto:nwc@u.washington.edu. Further information about the APEC Emerging Infections Network is available at http://www.apec.org/infectious.

Revised:
June 21, 2001

Contact us at apecein@u.washington.edu
© 2000, The University of Washington