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Vol. I, No. 6 ~~~ EINet News Briefs ~~~ 02㪚㫺


****A free service of the APEC Emerging Infections Network*****

The EINet listserv was created to foster discussion, networking, and collaboration in the area of emerging infectious diseases (EID's) among academicians, scientists, and policy makers in the Asia–Pacific region. We strongly encourage you to share their perspectives and experiences, as your participation directly contributes to the richness of the "electronic discussions" that occur. To respond to the listserv, use the reply function.


In this edition:

  1. Avian flu update
  2. Overview of infectious–disease information from Pro–MED and other sources
  3. APEC Emerging Infections Network Side Meeting at 14th APEC Industrial Science and Technology Working Group (ISTWG), Monday, March 16, 1998, Taipei
  4. How to add colleagues to the EINet listserv


1. AVIAN FLU UPDATE

INCREASED SURVEILLANCE FOR INFLUENZA SHOULD BE CONTINUED

The 14 member World Health Organization (WHO) team started on 16 January at Guangzhou and visited Guangdong Provincial Health Bureau, Guangzhou and Shenzhen Municipal Health Bureaus, four epidemic prevention stations, hospitals, influenza surveillance sites, poultry farms, a wholesale market and animal quarantine laboratories. While the team found no human case of influenza A(H5N1) virus infection in Guangdong during its mission, there is still need to maintain intensified levels of surveillance for at least six months, because of the potential risk of adaptation of the H5N1 virus to humans, which could lead to the transmission of a highly virulent strain from person to person, according to Dr Daniel Lavanchy, who heads the WHO programme on influenza surveillance. Levanchy noted, "We were very impressed with the high quality of the surveillance activities which had been implemented by the Chinese Government in December 1997 and January 1998. The number of specimens collected for virus isolation from patients exhibiting flu–like symptoms has increased from 20 to 1000 samples per month, while key influenza laboratories, which are part of WHO's global influenza surveillance network, are strengthening their capabilities."

The mission made more than 20 technical recommendations on surveillance in humans, and surveillance in animals, including laboratory surveillance. Recommendations include more training of staff, improved reporting of epidemiological data and expanding the scope for serological and virological investigations to include duck and geese and to cover more farms. Dr Yin Dakui, the Chinese Vice–Minister of Health, said that China would be extending its collaboration with WHO on influenza, including H5N1.

Authorities in Hong Kong will resume importation of chickens from mainland China on 7 February 1998. Requirements for this will include additional inspection, and blood testing at chicken farms prior to export with complementary testing for avian influenza upon arrival in Hong Kong. Chickens will be segregated from live ducks/other water fowl at all levels to minimise the risk of transmission of the H5N1 virus from live ducks/other water fowl to live chickens. WHO also stressed that there is no public health reason for other countries to ban the importation of chicken and chicken products from China, including Hong Kong. <WHO WER and Epidemiological Bulletin>



2. OVERVIEW OF INFECTIOUS–DISEASE INFORMATION FROM PROMED

Here is our weekly summary of relevant Asia–Pacific EID issues based on postings to the ProMED Electronic Network, which is a prototype for a communications system to monitor emerging infectious diseases globally as an initiative of the Federation of American Scientists (FAS) and co–sponsored by WHO. More information about PROMED can be acquired contacting the moderator. Please contact the moderator if you would like more any of the reports below:


ASIA

FIJI – DENGUE (09)

The estimated number of suspected cases of dengue fever has reached 4,500. In addition, there have been seven deaths due to suspected Dengue Haemorrhagic Fever (DHF) to date, all reported from CWM hospital in Suva.

PAPUA NEW GUINEA – JAPANESE ENCEPHALITIS – REQUEST FOR INFORMATION
16ם㫺

Two Japanese mosquito–borne viral encephalitis (JE) cases have been confirmed in two cases (from Kokonda and Ipoknai) in the North Fly District, Western Province, a first for Papua New Guinea. They were diagnosed at Rumginae Hospital by Dr. John Oakley late last year <WHO Collaborating Centre for Viral Diseases in SE Asia and Western Pacific. Increasing seroprevalence for antibodies against JE detected in the Rumginae area in recent years indicate that the disease is spreading. Infection rates are high in endemic areas during peak transmission times, with encephalitis resulting in 1 of 20 to 1,000 infections

Dr. Oakley has requested information on a cheaper means of obtaining vaccine against JE. He has been quoted AUD$240 for a course of JE–VAX from Sydney but has heard there is a new vaccine developed by US and Chinese researchers in China which is much cheaper. Can any one help?


AMERICAS

USA AND AMERICAS – HANTAVIRUS PULMONARY SYNDROME – UPDATE
14ם㫺

USA: Since Hantavirus Pulmonary Syndrome (HPS) was first recognized in May 1993, 177 U.S. case–patients from 29 states have been laboratory confirmed by CDC and have been added to the national HPS registry. Of these 177, 39 were identified retrospectively, with onset of illness prior to May 1993. To date, 19 case–patients with onset of illness in 1997 have been confirmed.

Cumulative descriptive demographic statistics for the 177 confirmed U.S. case–patients in the HPS registry:

Male: 108 (61%) White: 132 (75%) American Indian: 39 (22%), Black: 5, Asian: 1, Hispanic: 20 (11%)
Age: Mean=37 (11㫝) Died: 79 (45%)

Brian Hjelle (University of New Mexico) estimates that there have been more than 130 cases in Argentina since the 1980s, close to 30 from Chile, and at least 34 from Paraguay, plus more in Brazil and Uruguay and possibly one in Bolivia. This would bring the total to over 200, but PAHO would have the correct numbers.

In contrast to US cases, South American cases are much more likely to be clustered in families. Thus there continue to be familial clusters in Argentina and Chile, but none of the recent clusters can be clearly linked to interpersonal transmission, as was observed in the 1996㫹 summer outbreak in Argentina.


3. APEC EMERGING INFECTIONS SIDE MEETING

14th APEC Industrial Science and Technology Working Group (ISTWG)
Monday, March 16, 1998.

This will be a key discussion of the initiative for APEC cooperation in emerging infectious diseases! Delegates from health backgrounds or related to the Ministry of Health will be particularly useful for detailing the next steps in this important initiative, but discussion will be at a level appropriate for non–health specialists to participate in a valuable way. Some of the areas of cooperation we will discuss: finalization of the APEC framework for the initiative, potential next steps including the exchange of surveillance and prevention information on selected diseases, resource access to libraries, collaborative research educational/distance learning, and training. The side meeting will take place in the afternoon. Attendance must be coordinated through each science and technology delegation, so please contact the lead of your S&T delegation.


4. HOW TO LEAVE THIS LIST OR POST COMMENTS TO IT

The APEC EINet listserv was established to enhance collaboration among academicians and public health professionals in the area of emerging infections surveillance and control. Subscribers are encouraged to share their own material with their colleagues in the Asian–Pacific Rim by addressing comments to apec–ein@u.washington.edu. To subscribe or unsubscribe, please contact Nedra Floyd Pautler at pautler@u.washington.edu. Further information about the APEC Emerging Infections Network is available at http://www.apec.org/infectious.

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Revised:
June 25, 1998

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