Welcome to the Kelly Lab!

The role of human genetic variability in response to pharmaceuticals or xenobiotics (commonly referred to as pharmacogenomics and toxicogenomics, respectively) is a continually-expanding field of study. However, the ability to study the function of a single gene under normal or disease states is hampered by the large interindividual variability found in the human population. To control for environmental and genetic effects, we use inbred genetically-engineered mice to study human gene function in vivo.