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Projects Oral Testosterone for Male Hormonal Contraception
John K. Amory, M.D., M.P.H., Principal Investigator
This work is focused on the development of a safe, effective form of oral testosterone for the treatment of men with testosterone deficiency and for use as part of an oral testosterone-progestin combination oral hormonal contraceptive for men.
Hormonal Control of Human Spermatogenesis
William J. Bremner, M.D., Ph.D., Principal Investigator
Dr. Bremner's research focuses on control factors in the male reproductive
system, including the roles of luteinizing hormone and
follicle-stimulating hormone in controlling testicular function, the
effects of androgens in men, and the effects of aging on the reproductive
system. Goals of this research include the development of an effective,
reversible hormonal contraceptive for men and the treatment of disorders
of spermatogenesis.
Genetic Analysis of the Regulation and Execution of Spermatogenesis in
Mice
Robert E. Braun, Ph.D.,
Principal Investigator
Research projects are ongoing to study the genetic control
of germline stem cell maintenance, androgen regulation of
spermatogenesis, and posttranscriptional control of gene expression in
haploid spermatids.
http://research.jax.org/faculty/bob_braun.htm
Sertoli Cell Function
Michael D. Griswold, Ph.D., Principal Investigator
Dr. Griswold investigates the
influence of Sertoli cells on the process of germinal cell differentiation
and maturation, and specifically the action of glycoproteins secreted by
these cells.
http://www.wsu.edu/~crb/3FacultyPages/Griswold.html
Brain Genes Governing Reproduction
Robert A. Steiner, Ph.D., Principal Investigator
Research in this
lab is directed toward understanding the neuroendocrine mechanisms
governing reproduction, with focus on the regulation of neuropeptides,
their receptors, and intracellular signaling pathways involved in the
control of gonadotropin secretion and body-weight regulation.
http://depts.washington.edu/pbiopage/people_fac_page.php?fac_ID=30
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