ERIN E. FETSCH
Senior Fellow
University of Washington
HSB, Box K155
Seattle, WA 98195
1-5233
efetsch
Research Interest:
I am currently investigating the role of cyclic-diguanylate (c-diGMP) signaling in Salmonella enterica. The levels of c-diGMP in the cell are regulated by proteins containing GGDEF domains that act as diguanylate cyclases, and proteins containing EAL domains, that are believed to act as phosphodiesterases. C-diGMP is a widely distributed second messenger among many gram-negative and gram-positive bacteria, and has been shown to be involved in a number of functions including the transition from sessility to motility, regulation of cellulose synthesis and biofilm formation, and bacterial killing of macrophages.
Publications:
Erin E. Fetsch and Amy L. Davidson. Maltose transport through the inner membrane of E. coli. Front. Biosci. 2003, D652-60.
Erin E. Fetsch and Amy L. Davidson. Vanadate-catalyzed photocleavage of the signature motif of an ATP-binding cassette (ABC) transporter. Proc Natl Acad Sci U S A. 2002, 99(15):9685-90.
Special interests or Hobbies :
Hiking, biking, yoga, crocheting, and scuba diving
