Jasmonate, ubiquitin ligase-substrate coreceptors, and inositol polyphosphates!
November 27,2010
Laura Sheard, Xu Tan, and Haibin Mao have just published a paper in Nature reporting the structural mechanisms by which an important plant hormone, jasmonate, is sensed by a three-molecule co-receptor. Jasmonate signaling regulates wound and stress responses in plants and involves an F-box protein, COI1, as part of an SCF ubiquitin ligase complex. In this paper, Laura, Xu, and Haibin revealed that jasmonate is perceived by a co-receptor system consisting of the ubiquitin ligase COI1, its polypeptide substrate, JAZ proteins, and an unexpected inositol pentakisphosphate......