Uncategorized – University of Washington – Diabetes Research Center https://depts.washington.edu/diabetes Fostering and supporting both basic and clinical research in diabetes and related metabolic disorders Tue, 04 Oct 2022 20:24:25 +0000 en-US hourly 1 ITHS Translational Pilot Award – Call for Applications https://depts.washington.edu/diabetes/iths-translational-pilot-award/ Tue, 20 Aug 2019 18:11:53 +0000 http://depts.washington.edu/diabetes/?p=4526 @media only screen and (min-width: 1000px) and (max-width: 5000px){body.kc-css-system .kc-css-2955797{width: 100%;}}body.kc-css-system .kc-css-2784648 ,body.kc-css-system .kc-css-2784648 p{text-align: left;}

ITHS is offering a Translational Pilot Award with a Special Emphasis on Diabetes in conjunction with the Diabetes Research Center to support studies that address impactful research issues within the translational science spectrum, with the long-term goal of improving the health of patients with diabetes. The call for applications is available at: https://www.iths.org/investigators/funding/tpa-diabetes/rfa/

The application deadline is September 20, 2019.

Please share this information with anyone that may be interested in applying.  Thank you.

Sakeneh Zraika, PhD
Director of P&F Programs
UW Diabetes Research Center
phone: +1 206-768-5391
email: zraikas@uw.edu

]]> P&F and Mini-Grants Related to COVID-19 https://depts.washington.edu/diabetes/pf-and-mini-grants-related-to-covid-19/ Fri, 12 Nov 2021 18:30:18 +0000 https://depts.washington.edu/diabetes/?p=9144

NIH-funded Diabetes Research Centers (DRC) and Centers for Diabetes Translational Research (CDTR) are soliciting applications for National Pilot & Feasibility and Mini-Grant awards related to COVID-19.  These  awards are intended to foster collaborative efforts between investigators from two or more DRCs and/or CDTRs at different institutions.  Mini-grants provide funds for investigators to take advantage of the national DRC biomedical core services and/or to initiate collaborative projects with any of the CDTR programs. More details are provided in the RFAs below. Applications are due February 1, 2022.

P&F RFA

P&F Budget Form

Mini-grants RFA

]]> Studies Show Increasing Prevalence of Type 1 and Type 2 Diabetes in Youth and Increased Risk of Diabetic Complications in Youth with Type 2 Diabetes https://depts.washington.edu/diabetes/studies-show-increasing-prevalence-of-type-1-and-type-2-diabetes-in-youth-and-increased-risk-of-diabetic-complications-in-youth-with-type-2-diabetes/ Mon, 24 Apr 2017 19:42:12 +0000 http://depts.washington.edu/diabetes/?p=2249 @media only screen and (min-width: 1000px) and (max-width: 5000px){body.kc-css-system .kc-css-346490{width: 29.62%;}body.kc-css-system .kc-css-1945172{width: 70.36%;}}body.kc-css-system .kc-css-913048 ,body.kc-css-system .kc-css-913048 p{text-align: left;}

Catherine Pihoker and Santica Marcovina, two UW Diabetes Research Center affiliates, are authors on recent papers highlighting diabetes in youth. In the one study published in The New England Journal of Medicine on April 13, using data from the ongoing SEARCH for Diabetes in Youth study they and their colleagues showed that between 2002 and 2012 the adjusted relative incidence rates of type 1 and type 2 diabetes among US youth had increased annually 1.8% and 4.8%, respectively. The highest annual rate of increase for type 1 diabetes was among Hispanic youth and among Native American youth for type 2 diabetes. The second study also used data from SEARCH for Diabetes in Youth study and was published on February 28 in The Journal of the American Medical Association. In this study, it was found that in 1,746 youth with type 1 diabetes and 272 with type 2 diabetes who had been followed for an average of 7.9 years, both groups had diabetic complications. Those with type 2 diabetes had a greater risk of developing diabetic kidney disease, retinopathy and peripheral neuropathy than those with type 1 diabetes.

]]> Affiliate Jonathan Himmelfarb Receives Two New NIDDK Awards for the Kidney Precision Medicine Project https://depts.washington.edu/diabetes/affiliate-jonathan-himmelfarb-receives-two-new-niddk-awards-for-the-kidney-precision-medicine-project/ Mon, 03 Oct 2022 22:03:38 +0000 https://depts.washington.edu/diabetes/?p=12282 @media only screen and (min-width: 1000px) and (max-width: 5000px){body.kc-css-system .kc-css-1251580{width: 100%;}}

Affiliate professor Jonathan Himmelfarb is collaborating with Matthias Kretzler (University of Michigan) as co-Principal Investigators for two new awards totaling $30.8 million from NIH’s National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) for the Kidney Precision Medicine Project (KPMP). KPMP is an ambitious, multi-year collaboration of more than 40 leading research institutions across the United States to create a kidney tissue atlas that will help understand the mechanisms of acute kidney injury (AKI) and chronic kidney disease (CKD), define new disease subgroups, and identify cell states and pathways for new therapeutic targets.

]]> Markers of Islet Endothelial Dysfunction Occur in Male B6.BKS(D)-Leprdb/J Mice and May Contribute to Reduced Insulin Release https://depts.washington.edu/diabetes/markers-of-islet-endothelial-dysfunction-occur-in-male-b6-bksd-leprdbj-mice-and-may-contribute-to-reduced-insulin-release/ Thu, 30 Mar 2017 20:37:56 +0000 http://depts.washington.edu/diabetes/?p=2073 @media only screen and (min-width: 1000px) and (max-width: 5000px){body.kc-css-system .kc-css-1048660{width: 29.62%;}body.kc-css-system .kc-css-592736{width: 70.36%;}}body.kc-css-system .kc-css-3164683 ,body.kc-css-system .kc-css-3164683 p{text-align: left;}

Editor’s pick: Meghan Hogan, Amy Liu, Rebecca Hull and colleagues authored the featured paper in Endocrinology in February.  Their work described in this article highlights that under conditions of hyperglycemia, islet endothelial cells are dysfunctional and that this dysfunction may be an important contributor to the secretory abnormalities observed in diabetes.

Markers of Islet Endothelial Dysfunction Occur in Male B6.BKS(D)-Leprdb/J Mice and May Contribute to Reduced Insulin Release

]]>