Breast cancer
Deafness
Schizophrenia & neural genetic disorders
Other phenotypes
Human rights/human identification
Gene structure, diversity, and evolution
Other publications
Breast/ovarian cancer:
Walsh T, Casadei S, Lee MK, Pennil CC, Nord AS, Thornton AM, Roeb W, Agnew KJ, Stray SM, Wickramanayake A, Norquist B, Pennington KP, Garcia RL, King MC, Swisher EM. 2011. Mutations in 12 genes for inherited ovarian, fallopian tube, and peritoneal carcinoma identified by massively parallel sequencing. Proc Natl Acad Sci U S A. 108(44):18032-7. Epub 2011 Oct 17.
Casadei S, Norquist BM, Walsh T, Stray SM, Mandell JB, Lee MK, Stamatoyannopoulos JA, King MC. 2011. Contribution to Familial Breast Cancer of Inherited Mutations in the BRCA2-interacting Protein PALB2. Cancer Res. 2011 Feb 1. [Epub ahead of print]
Peixoto A, Santos C, Pinheiro M, Pinto P, Soares MJ, Rocha P, Gusmăo L, Amorim A, van der Hout A, Gerdes AM, Thomassen M, Kruse TA, Cruger D, Sunde L, Bignon YJ, Uhrhammer N, Cornil L, Rouleau E, Lidereau R, Yannoukakos D, Pertesi M, Narod S, Royer R, Costa MM, Lazaro C, Feliubadaló L, Grańa B, Blanco I, de la Hoya M, Caldés T, Maillet P, Benais-Pont G, Pardo B, Laitman Y, Friedman E, Velasco EA, Durán M, Miramar MD, Valle AR, Calvo MT, Vega A, Blanco A, Diez O, Gutiérrez-Enríquez S, Balmańa J, Ramon Y Cajal T, Alonso C, Baiget M, Foulkes W, Tischkowitz M, Kyle R, Sabbaghian N, Ashton-Prolla P, Ewald IP, Rajkumar T, Mota-Vieira L, Giannini G, Gulino A, Achatz MI, Carraro DM, de Paillerets BB, Remenieras A, Benson C, Casadei S, King MC, Teugels E, Teixeira MR. 2010. International distribution and age estimation of the Portuguese BRCA2 c.156_157insAlu founder mutation. Breast Cancer Res Treat. 2010 Jul 22. [Epub ahead of print]
Walsh T, Lee MK, Casadei S, Thornton AM, Stray SM, Pennil C, Nord AS, Mandell JB, Swisher EM, King MC. 2010. Detection of inherited mutations for breast and ovarian cancer using genomic capture and massively parallel sequencing. Proc Natl Acad Sci U S A. 107:12629-33. Epub 2010 Jun 28.
Chisholm KM, Goff BA, Garcia R, King MC, Swisher EM. 2008. Genomic structure of chromsome 17 deletions in BRCA1-associated ovarian cancers. Cancer Genet Cytogenet. 183(1):41-8.
Swisher EM, King MC. 2007. Defining women at high risk of ovarian cancer. Cancer Res. 67(6):2902.
Walsh T, King MC. 2007. Ten genes for inherited breast cancer. Cancer Cell. 11(2):103-5.
DelloRusso C, Welcsh PL, Wang W, Garcia RL, King MC, Swisher EM. 2007. Functional characterization of a novel BRCA1-null ovarian cancer cell line in response to ionizing radiation. Mol Cancer Res. 5(1):35-45.
Walsh T, Casadei S, Coats KH, Swisher E, Stray SM, Higgins J, Roach KC, Mandell J, Lee MK, Ciernikova S, Foretova L, Soucek P, King MC. 2006. Spectrum of mutations in BRCA1, BRCA2, CHEK2, and TP53 in families at high risk of breast cancer. JAMA 295:1379-88.
Simchoni S, Friedman E, Kaufman B, Gershoni-Baruch R, Orr-Urtreger A, Kedar-Barnes I, Shiri-Sverdlov R, Dagan E, Tsabari S, Shohat M, Catane R, King MC, Lahad A, Levy-Lahad E. 2006. Familial clustering of site-specific cancer risks associated with BRCA1 and BRCA2 mutations in the Ashkenazi Jewish population. Proc Natl Acad Sci U S A. 103:3770-4.
Gallardo M, Silva A, Rubio L, Alvarez C, Torrealba C, Salinas M, Tapia T, Faundez P, Palma L, Riccio ME, Paredes H, Rodriguez M, Cruz A, Rousseau C, King MC, Camus M, Alvarez M, Carvallo P. 2005. Incidence of BRCA1 and BRCA2 mutations in 54 Chilean families with breast/ovarian cancer, genotype-phenotype correlations. Breast Cancer Res Treat. Oct 27;:1-7 [Epub ahead of print].
Swisher EM, Wollan M, Mahtani SM, Willner JB, Garcia R, Goff BA, King MC. 2005. Tumor-specific p53 sequences in blood and peritoneal fluid of women with epithelial ovarian cancer. Am J Obstet Gynecol. 193(3 Pt 1):662-7.
Shaag A, Walsh T, Renbaum P, Kirchhoff T, Nafa K, Shiovitz S, Mandell JB, Welcsh P, Lee MK, Ellis N, Offit K, Levy-Lahad E, King MC. 2005. Functional and genomic approaches reveal an ancient CHEK2 allele associated with breast cancer in the Ashkenazi Jewish population. Human Molecular Genetics 2005 14(4):555-563.
King MC. 2004. A novel BRCA2-binding protein and breast and ovarian tumorigenesis. N Engl J Med. 350(12):1252-3.
King MC, Marks JH, Mandell JB; New York Breast Cancer Study Group. 2003. Breast and ovarian cancer risks due to inherited mutations in BRCA1 and BRCA2. Science 302:643-6.
Hamaguchi M, Meth JL, von Klitzing C, Wei W, Esposito D, Rodgers L, Walsh T, Welcsh P, King MC, Wigler MH. 2002. DBC2, a candidate for a tumor suppressor gene involved in breast cancer. Proc Natl Acad Sci U S A. 99:13647-52.
Welcsh PL, Lee MK, Gonzalez-Hernandez RM, Black DJ, Mahadevappa M, Swisher EM, Warrington JA, King MC. 2002. BRCA1 transcriptionally regulates genes involved in breast tumorigenesis. Proc Natl Acad Sci U S A. 99:7560-5.
King MC, Wieands, Hale K, Lee MK, Walsh T, Owens K, Tait J, Ford L, Constantino J, Wickerham L, Wolmark N, Fisher B. 2001. Tamoifen and breast cancer incidence among women with inherited mutations in BRCA1 and BRCA2 from the NSABP-P1 Breast Cancer Prevention Trial. J Amer Med Assoc 286: 2251-56.
Brzovic PS, Meza JE, King MC, Klevit RE. 2001. BRCA1 RING domain cancer-presidposing mutations: structural consequences and effects on protein-protein interactions. J Biol Chem 276:41399-406.
Brzovic PS, Rajagopal P, Hoyt DW, King MC, Klevit RE. 2001. Structure of a BRCA1-BARD1 heterodimeric RING-RING complex. Nat Struct Biol. 8:833-7.
Welcsh PL, King MC. 2001. BRCA1 and BRCA2 and the genetics of breast and ovarian cancer. Hum Mol Genet 10:705-13.
Berger C, Pierce LN, Kruger M, Marcusson EG, Robbins JM, Welcsh P, Welch PJ, Welte K, King MC, Barber JR, Wong-Staal F. 001. Identification of Id4 as a regulator of BRCA1 expression by using a ribozyme-library-based inverse genomics approach. Proc Natl Acad Sci USA 98:130-5.
Welcsh PL, Owens K, King MC. 2000. Insights into the functions of BRCA1 and BRCA2. Trends Genet 16:69-74.
Liede A, Cohen B, Black DM, Davidson RH, Renwick A, Hoodfar E, Olopade OI, Micek M, Anderson V, DeMay R, Fordyce A, Warner E, Dnan JL, King MC, Weber B, Narod SS, Steel CM. 2000. Evidence of a founder BRCA1 mutation in Scotland. Brit J Cancer 82:705-711.
Payne SR, Newman B, King MC. 2000. Complex germline rearrangement of BRCA1 associated with breast and ovarian cancer. Genes, Chromosomes, Cancer 29:58-62.
Van der Looij M, Szabo C, Besznyak I, Listzka G, Csokay B, Pulay T, Toth J, Devilee P, King MC, Olah E. 2000. Prevalence of founder BRCA1 and BRCA2 mutations among breast and ovarian cancer patients in Hungary. Int J Cancer 86:737-740.
Schubert EL, Lee MK, Newman B, King M-C. 1999. Single nucleotide polymorphisms (SNPs) in the estrogen receptor gene and breast cancer susceptibility. J Ster Biochem Mol Biol 71:21-27.
Breast Cancer Linkage Consortium. 1999. Cancer risks in BRCA2 mutation carriers. J Natl Cancer Inst 91:1310-1316.
Mefford HC, Baumbach L, Panguluri RCK, Whitfield-Broome C, Szabo C, Smith S, King M-C, Dunston G, Stoppa-Lyonnet D, Arena F. 1999. Evidence for a BRCA1 founder mutation in families of West African ancestry. Amer J Hum Genet 65:575-578.
Meza JE, Brzovic PS, King M-C, Klevit RE. 1999. Mapping the functional domains of BRCA1. Interaction of the ring finger domains of BRCA1 and BARD1. J Biol Chem 274:5659-5665.
Welcsh PL, Schubert EL, King MC. 1998. Inherited breast cancer: an emerging picture. Clin Genet 54:447-58.
Redston M, Nathanson KL, Yuan ZQ, Neuhausen SL, Satagopan J, Wong N, Yang D, Nafa D, Abrahamson J, Ozcelik H, Antin-Ozerkis D, Andrulis I, Daly M, Pinsky L, Schrag D, Gallinger S, Kaback M, King MC, Woodage T, Brody LC, Godwin A, Warner E, Weber B, Foulkes W, Offit K. 1998. The APCI1307K allele and breast cancer risk. Nature Genet 20:13-14.
Neuhausen SL, Godwin AK, Gershoni-Baruch R, Schubert E, Garber J, Stoppa-Lyonnet D, Olah E, Csokay B, Serova O, Lalloo F, Osorio A, Stratton M, Offit K, Boyd J, Caligo MA, Scott RJ, Schofield A, Teugels E, Schwab M, Cannon-Albright L, Bishop T, Easton D, Benitez J, King MC, Goldgar D, et al. 1998. Haplotype and phenotype analysis of nine recurrent BRCA2 mutations in 111 families: Results of an international study. Amer J Hum Genet 62:1381-1388.
Brzovic PS, Meza J, King M-C, Klevit RE. 1998. The cancer-predisposing mutation C61G disrupts homodimer formation in the N-terminal BRCA1 RING-finger domain. J Biol Chem 273:7795-7799.
Tait DL, Jensen RA, Holt JT, Johnson DH, Gralow J, King MC. 1998. Gene therapy for breast and ovarian cancer with BRCA1. Breast Dis. 10:89-98.
Newman B, Mu H, Butler LM, Millikan RC, Moorman PG, King M-C. 1998. Frequency of breast cancer attributable to BRCA1 in a population-based series of American women. J Amer Med Assoc 279:915-921.
Lynch ED, Ostermeyer EA, Lee MK, Arena JF, Ji HL, Dann J, Swisshelm K, Suchard D, MacLeod PM, Kvinnsland S, Gjertsen BT, Heimdal K, Lubs H, Moller P, King M-C. 1997. Inherited mutations in PTEN associated with breast cancer, Cowden Disease, and juvenile polyposis. Amer J Human Genet 61:1254-1260.
Tait DL, Obermiller PS, Redlin-Frazier S, Jensen RA, Welcsh P, Dann J, King, M-C, Johnson DH, Holt JT. 1997. A phase I trial of retroviral BRCA1 gene therapy for ovarian cancer. Clinical Cancer Research 3:1959-1968.
Szabo CI, King M-C. 1997. Population genetics of BRCA1 and BRCA2. Amer J Human Genet 60:1013-1020.
Schubert EL, Lee MK, Mefford HC, Argonza RH, Morrow JE, Hull J, Dann JL, King M-C. 1997. BRCA2 in American families with four or more cases of breast or ovarian cancer: Recurrent and novel mutations, variable expression, penetrance, and the possibility of families whose cancer is not attributable to BRCA1 or BRCA2. Amer J Human Genet 60: 1031-1040.
Newman B, Millikan RC, King M-C. 1997. Genetic epidemiology of breast and ovarian cancers. Epidemiol Rev 19:69-79.
Abel KJ, Brody LC, Valdes JM, Erdos MR, McKinley DR, Castilla LH, Merajver SD, Couch FJ, Friedman LS, Ostermeyer EA, Lynch ED, King MC, Welcsh PL, Osborne-Lawrence SO, Spillman M, Bowcock AM, Collins FS, Weber BL. 1996. Characterization of EZH1, a human homolog of Drosophila Enhancer of zeste near BRCA1. Genomics 37:161-171.
Smith TM, Lee M, Szabo CI, Jerome N, McEuen M, Taylor M, Hood L, King M-C. 1996. complete genomic sequence and analysis of 117 kb of human DNA containing the gene BRCA1. Genome Res 6:1029-1049.
Szabo CI, Wagner LA, Francisco LV, Roach J, Argonza R, King M-C, Ostrander EA. 1996. Human, canine and murine BRCA1 genes: Sequence comparison among species. Human Molec Genet 9:1289-1298.
Jensen RA, Thompson ME, Jetton TL, van der Meer R, Helou B, Arteaga CL, Page DL, Holt JT, Tronick SR, Gown AM, Skelly M, Ostermeyer B, Schieltz D, Szabo CI, King M-C. 1996. BRCA1 protein products: Antibody specificity, functional motifs, and secreted tumor suppressors. Nature Genet 13:269-272.
Holt JT, Thompson ME, Szabo CI, Robinson-Benion C, Arteaga CL, King M-C, Jensen RA. 1996. Growth retardation and tumor inhibition by BRCA1. Nature Genet 12:298-302. 132. Szabo CI, King M-C. 1995. Inherited breast and ovarian cancer. Human Molec Genet 4:1811-1817.
Jensen RA, Thompson ME, Jetton TL, Szabo CI, van der Meer R, Helou B, Tronick SR, Page DL, King M-C, Holt JT. 1996. BRCA1 is secreted and exhibits properties of a granin. Nature Genet 12:303-308.
Johannsson O, Ostermeyer EA, Hakansson S, Friedman LS, Johansson U, Sellberg G, Brondum-Nielsen K, Sele V, Olsson H, King M-C, Borg A. 1996. Founding BRCA1 mutations in hereditary breast and ovarian cancer in southern Sweden. Amer J Human Genet 58:441-450.
Neuhausen SL, Mazoyer S, Friedman LS, Stratton M, Offit K, Caligo A, Tomlinson G, Cannon-Albright L, Bishop T, Kelsell D, Solomon E, Weber B, Couch F, Struewing J, Tonin P, Durocher F, Narod S, Skolnick M, Lenoir G, Serova O, Ponder B, Stoppa-Lyonnet D, Easton D, King M-C, Goldgar DE. 1996. Haplotype and phenotype analysis of six recurrent BRCA1 mutations in 61 families: Results of an international study. Amer J Human Genet 58:271-280.
Friedman LS, Szabo CI, Ostermeyer EA, Dowd P, Butler L, Park T, Lee MK, Goode EL, Rowell SE, King M-C. 1995. Novel inherited mutations and variable expressivity of BRCA1 alleles, including the founder mutation in Ashkenazi Jewish families. Amer J Human Genet 57:1284-1297.
Takahashi H, Behbakht K, McGovern PE, Chiu HC, Couch FJ, Weber BL, Friedman LS, King M-C, Furusato M, LiVolsi VA, Menzin A, Liu P, Benjamin I, Morgan MA, King SA, Rebane BA, Cardonick A, Mikuta JJ, Rubin SC, Boyd J. 1995. Mutation analysis of the BRCA1 gene in ovarian cancers. Cancer Res 55:2998-3002.
Shattuck-Eidens D et al. (42 authors). 1995. A collaborative survey of 80 mutations in the BRCA1 breast and ovarian cancer susceptibility gene. J Amer Med Assoc 273:535-541.
Ostermeyer EA, Friedman LS, Lynch ED, Szabo CI, Dowd P, Lee MK, Rowell SE, King M-C. 1994. Green pigs, red herrings, and a golden hoe: a retrospective on the identification of BRCA1 and the beginning of its characterization. Cold Spr Harb Lab Symp Quant Biol 59:523-530.
Couch FJ, Castilla LH, Xu J, Abel KJ, Welcsh P, King SE, Wong L, Ho PP, Merajver S, Brody LC, Yin GY, Hayes ST, Geiser LM, Flejter WL, Glover TW, Friedman LS, Lynch ED, Meza JE, King M-C, Law DJ, Deaven L, Bowcock AM, Collins FS, Weber BL, Chandrasekharappa SC. 1995. A YAC, P1, and cosmid-based physical map of the BRCA1 region on chromosome 17q21. Genomics 25:264-273.
Friedman LS, Ostermeyer EA, Lynch ED, Szabo CI, Meza JE, Anderson LA, Dowd P, Lee MK, Rowell SE, Ellison J, Boyd J, King M-C. 1995. 22 genes from chromosome 17q21: Cloning, sequencing, and characterization of mutations in breast cancer families and tumors. Genomics 25:256-263.
Friedman LS, Ostermeyer EA, Szabo CI, Dowd P, Lynch ED, Rowell SE, King M-C. 1994. Confirmation of BRCA1 by analysis of germline mutations linked to breast and ovarian cancer in ten families. Nature Genet 8:399-404.
Friedman LS, Ostermeyer EA, Lynch ED, Szabo CI, Anderson LA, Dowd P, Lee MK, Rowell SE, Boyd J, King M-C. 1994. The search for BRCA1. Cancer Res 54:6374-6382.
Rowell S, Newman B, Boyd J, King M-C. 1994. Inherited predisposition to breast and ovarian cancer. (Editorial) Amer J Human Genet 55:861-865.
King MC, Rowell S. 1994. Genetic analysis of breast and ovarian cancer in families. Cancer Treat Res 71:51-62.
Stratton MR, Ford D, Neuhasen S, Seal S, Wooster R, Friedman LS, King MC, Egilsson V, Devilee P, McManus R, Daly PA, Smyth E, Ponder BAJ, Peto J, Cannon-Albright L, Easton DF, Goldgar DE. 1994. Familial male breast cancer is not linked to the BRCA1 locus on chromosome 17q. Nature Genet 7:103-107.
King M-C, Rowell SE, Love SM. 1993. Inherited breast and ovarian cancer: What are the risks? What are the choices? J Amer Med Assoc 269:1975-1980.
Ginther C, Corach D, Penacino GA, Rey JA, Carnese FR, Hutz MH, Anderson A, Just J, Salzano FM, King M-C. 1993. Genetic variation among the Mapuche Indians from the Patagonian region of Argentina: mitochondrial DNA sequence variation and allele frequencies of several nuclear genes. EXS 67:211-219.
Anderson LA, Friedman LS, Osborne-Lawrence S, Lynch ED, Weissenbach J, Bowcock AM, King M-C. 1993. High-density genetic map of the BRCA1 region of chromosome 17q12-q21. Genomics 17:616-623.
Bowcock AM, Anderson LA, Friedman LS, Black DM, Osborne-Lawrence S, Rowell SE, Hall JM, Solomon E, King M-C. 1993. Polymorphisms in THRA1 and D17S183 flank an interval of <4 cM for the breast-ovarian cancer gene on chromosome 17q. Amer J Human Genet 52:718-722.
King M-C. 1992. Breast cancer genes: How many, where, and who are they? (Editorial.) Nature Genet 2:125-126.
Margaritte P, Bonaiti-Pellie C, King M-C, Clerget-Darpoux F. 1992. Linkage of familial breast cancer to chromosome 17q21 may not be restricted to early-onset disease. Amer J Human Genet 50:1231-1234.
Hall JM, Friedman L, Guenther C, Lee MK, Weber JL, Black DM, King MC. 1992. Closing in on a breast cancer gene on chromosome 17q. Amer J Human Genet 50:1235-1242.
Merette C, King MC, Ott J. 1992. Heterogeneity analysis of breast cancer families by using age at onset as a covariate. Amer J Human Genet 50:515-519.
Zuppan PJ, Hall JM, Lee MK, Ponglikitmongkol M, King MC. 1991. Possible linkage of the estrogen receptor gene to breast cancer in a family with late-onset disease. Amer J Human Genet 48:1065-1068.
King MC. 1991. Genetic analysis of cancer in families. Cancer Surv 9:417-435.
Hall JM, Lee MK, Morrow J, Newman B, Anderson LA, Huey B, King MC. 1990. Linkage of early-onset familial breast cancer to chromosome 17q21. Science 250:1684-1689.
Bowcock AM, Hall JM, Hebert JM, King MC. 1990. Exclusion of the retinoblastoma gene and chromosome 13q as the site of a primary lesion for human breast cancer. Amer J Human Genet 46:12-17.
Hall JM, Huey B, Morrow J, Newman B, Jones E, Carter C, Buehring GC, King MC. 1990. Rare HRAS alleles and susceptibility to human breast cancer. Genomics 6:188-191.
Hall JM, Doohan J, King M-C. 1989. Exclusion of chromosome 17p as the site of a primary lesion for human breast cancer. Cyto Genet Cell Genet 51: 1010.
Hall JM, Zuppan P, Anderson LA, Huey B, Carter C, King MC. 1989. Oncogenes and human breast cancer. Amer J Human Genet 44:577-584.
Newman B, Austin MA, Lee M, King MC. 1988. Inheritance of human breast cancer: Evidence for autosomal dominant transmission in high-risk families. Proc Natl Acad Sci USA 85:3044-3048.
Hall J, Tikochinski Y, Huey B, Morrow J, Louie L, Newman B, King MC. 1987. Genetic analysis of human breast cancer in an extended family using candidate genes and minisatellite sequences. Cyto Genet Cell Genet 46:626.
Hall J, Huey B, Morrow J, King MC. 1987. Polymorphisms of EGFR and INT2, candidate loci for human breast cancer. Cyto Genet Cell Genet 46:625.
Wilson AF, Bailey-Wilson JE, Cleton FJ, Elston RC, King MC. 1987. Genetic analysis of Dutch families at high risk for breast cancer. Genet Epidemiol 3:87-92 .
King MC, Cannon LA, Bailey-Wilson JE. 1987. Genetic analysis of human breast cancer: Literature review and description of family data in workshop. Genet Epidemiol 3:3-14.
Bailey-Wilson JE, Cannon LA, King MC. 1987. Genetic analysis of human breast cancer: A synthesis of contributions to Genetic Analysis Workshop IV. Genet Epidemiol 3:15-36.
King MC. 1987. Familial breast cancer and the awareness bias: one of the authors replies. (Letter to the editor) Amer J Epidemiol 125:920-921.
King MC. Of mice and women. 1986. In Breast Cancer: Origins, Detection and Treatment. M Rich et al. (eds). Martinus-Nijhoff, Boston, pp. 227-236.
Ottman R, Pike MC, King MC, Casagrande JT, Henderson BE. 1985. Familial breast cancer in a population-based series. Amer J Epidemiol 123:15-21.
Schwartz AG, King MC, Belle SH, Satariano WA, Swanson GM. 1985. Risk of breast cancer to relatives of young breast cancer patients. J Natl Cancer Inst 75:665-668.
King MC, Elston RC. 1985. Genetic epidemiology of breast cancer: A comment on heterogeneity. Genet Epidemiol 2:167-169.
King MC. 1985. Breast cancer genetics: Definition of risk, patterns of inheritance, and management of patients and family members. In Breast Disease, JF Forbes (ed), Churchill Livingston, pp. 82-94.
King MC. 1985. Genetic epidemiology of human cancer: Application to familial breast cancer. In Genetics in Clinical Oncology. RSK Chaganti and J German (eds), Oxford Univ Press, New York. pp. 122-132.
Odenheimer D, Zunzunegui MV, Shipler C, King MC, Friedman GD. 1984. Risk factors for benign breast disease: A case-control study of discordant twins. Amer J Epidemiol 120:565-571.
Ottman R, Pike MC, King MC, Henderson BE. 1983. Estimating risk for familial breast cancer: A practical guide. Lancet ii:556-558.
Cleton FJ, deJong-Bakker M, King MC. 1983. Genetic analysis of breast cancer in Dutch families. European Org Res Treat Cancer 2:11.
King MC, Go RCP, Lynch HT, Elston RC, Lynch HT, Terasaki PT, Petrakis L, Rodgers GC, Lattanzio D, Bailey-Wilson J. 1983. Genetic epidemiology of breast cancer in high-risk families. II. Linkage analysis. J Natl Cancer Inst 71:463-467.
Go RCP, King MC, Bailey-Wilson J, Elston RC, Lynch HT. 1983. Genet Epid of breast cancer in high risk families. I. Segregation analysis. J Natl Cancer Inst 71:455-461.
King MC. 1982. Genetic and epidemiologic analysis of cancer in families. Cancer Surveys 1:33-46.
Petrakis NL. Ernster VL, King MC. 1982. Epidemiology of breast cancer. In Cancer Epidemiology and Prevention. Schottenfeld D and Fraumeni JF (eds). Saunders, Philadelphia, pp. 855-870.
Petrakis NL, Ernster VL, Sacks ST, King EB, Schweitzer RJ, Hunt TK, King MC. 1981. The epidemiology of breast fluid secretion: Association with breast cancer risk factors and cerumen type. J Natl Cancer Inst 67:227-284.
King MC. 1981. Risk factors for breast cancer. Science 214:1122-1123.
King MC. 1980. Genet Epid of human cancer. In Cancer 1980: Progress and Prospects, Vol. 1, Grune & Stratton, New York, pp. 397-406.
Elston RC, Go RCP, King MC, Lynch HT. 1980. A statistical model for the study of familial breast cancer. In Genetics and Breast Cancer, HT Lynch (ed). Van Nostrand, New York, pp. 49-64.
King MC, Petrakis NL. 1980. Genetic and socioeconomic risk factors for breast cancer among black women in northern California. Amer J Epidemiol 112:429-430.
King MC, Bishop DT. 1980. Preliminary analysis of linkage of glutamate-pyruvate transaminase and breast cancer susceptibility in a Mormon kindred. In Banbury Report 4: Cancer Incidence in Defined Populations, Cold Spr Harbor Lab, New York, 379-385.
King MC, Go RCP, Elston RC, Lynch HT, Petrakis NL. 1980. An allele increasing susceptibility to human breast cancer may be linked to the GPT locus. Science 208:406-408.
King MC, Lynch HT, Selvin S. 1979. Laterality of breast cancer in families. Amer J Epidemiol 110:88-98.
King EB, Zimmerman LA, Barrett DL, Petrakis NL, King MC. 1979. Cytopathology of abnormal mammary duct epithelium. Prevent Detect Cancer 2:1183-1845.
King MC. 1979. Multiple factors in breast cancer risk. Prevent Detect Cancer 2:1551-1558.
Lynch HT, et al. 1977. HLA in breast-cancer prone families and the cancer family syndrome. Prog Clin Biol Res 16:149-162.
Petrakis NL, King MC. 1977. Genetic markers and cancer epidemiology. Cancer 39:1861-1866.
King MC, Petrakis NL. 1977. Genetic markers and cancer. Prog Cancer Res Ther 3:281-290.
Deafness:
Brownstein Z, Friedman LM, Shahin H, Oron-Karni V, Kol N, Rayyan AA, Parzefall T, Lev D, Shalev S, Frydman M, Davidov B, Shohat M, Rahile M, Lieberman S, Levy-Lahad E, Lee MK, Shomron N, King MC, Walsh T, Kanaan M, Avraham KB. 2011. Targeted genomic capture and massively parallel sequencing to identify genes for hereditary hearing loss in middle eastern families. Genome Biol.12(9):R89. [Epub ahead of print]
Walsh VL, Raviv D, Dror AA, Shahin H, Walsh T, Kanaan MN, Avraham KB, King MC. 2010. A mouse model for human hearing loss DFNB30 due to loss of function of myosin IIIA. Mamm Genome. 2010 Dec 17. [Epub ahead of print]
Sirmaci A, Walsh T, Akay H, Spiliopoulos M, Sakalar YB, Hasanefendio?lu-Bayrak A, Duman D, Farooq A, King MC, Tekin M. 2010. MASP1 mutations in patients with facial, umbilical, coccygeal, and auditory findings of Carnevale, Malpuech, OSA, and Michels syndromes. Am J Hum Genet. 87:679-86. Epub 2010 Oct 28.
Pierce SB, Walsh T, Chisholm KM, Lee MK, Thornton AM, Fiumara A, Opitz JM, Levy-Lahad E, Klevit RE, King MC. 2010. Mutations in the DBP-deficiency protein HSD17B4 cause ovarian dysgenesis, hearing loss, and ataxia of Perrault Syndrome. Am J Hum Genet. 87:282-8. Epub 2010 Jul 30.
Walsh T, Pierce SB, Lenz DR, Brownstein Z, Dagan-Rosenfeld O, Shahin H, Roeb W, McCarthy S, Nord AS, Gordon CR, Ben-Neriah Z, Sebat J, Kanaan M, Lee MK, Frydman M, King MC, Avraham KB. 2010. Genomic duplication and overexpression of TJP2/ZO-2 leads to altered expression of apoptosis genes in progressive nonsyndromic hearing loss DFNA51. Am J Hum Genet.87:101-9. Epub 2010 Jun 17.
Walsh T, Shahin H, Elkan-Miller T, Lee MK, Thornton AM, Roeb W, Abu Rayyan A, Loulus S, Avraham KB, King MC, Kanaan M. 2010. Whole exome sequencing and homozygosity mapping identify mutation in the cell polarity protein GPSM2 as the cause of nonsyndromic hearing loss DFNB82. Am J Hum Genet. 87:90-4. Epub 2010 Jun 17.
Shahin H, Rahil M, Abu Rayan A, Avraham KB, King MC, Kanaan M, Walsh T. 2010. Nonsense mutation of the stereociliar membrane protein gene PTPRQ in human hearing loss DFNB84. J Med Genet. 47:643-5. Epub 2010 May 14.
Sirmaci A, Erbek S, Price J, Huang M, Duman D, Cengiz FB, Bademci G, Tokgöz-Yilmaz S, Hi?mi B, Ozda? H, Oztürk B, Kulaksizo?lu S, Yildirim E, Kokotas H, Grigoriadou M, Petersen MB, Shahin H, Kanaan M, King MC, Chen ZY, Blanton SH, Liu XZ, Zuchner S, Akar N, Tekin M. 2010. A truncating mutation in SERPINB6 is associated with autosomal-recessive nonsyndromic sensorineural hearing loss. Am J Hum Genet. 86:797-804. Epub 2010 May 6.
Shahin H, Walsh T, Rayyan AA, Lee MK, Higgins J, Dickel D, Lewis K, Thompson J, Baker C, Nord AS, Stray S, Gurwitz D, Avraham KB, King MC, Kanaan M. 2010. Five novel loci for inherited hearing loss mapped by SNP-based homozygosity profiles in Palestinian families. Eur J Hum Genet. 18:407-13. Epub 2009 Nov 4.
Doucette L, Merner ND, Cooke S, Ives E, Galutira D, Walsh V, Walsh T, MacLaren L, Cater T, Fernandez B, Green JS, Wilcox ER, Shotland L, Li XC, Lee M, King MC, Young TL. 2009. Profound, prelingual nonsyndromic deafness maps to chromosome 10q21 and is caused by a novel missense mutation in the Usher syndrome type IF gene PCDH15. European Journal of Human Genetics 17:554.
Shahin H, Walsh T, Sobe T, Abu Sa'ed J, Abu Rayan A, Lynch ED, Lee MK, Avraham KB, King MC, and Kanaan M. 2006. Mutations in a Novel Isoform of TRIOBP that Encodes a Filamentous-Actin Binding Protein are Responsible for DFNB28 Recessive Non-Syndromic Hearing Loss. Am J Hum Genet, 78:144-52.
Walsh T, Abu Rayan A, Abu Sa'ed J, Shahin H, Shepshelovich J, Lee MK, Hirschberg K, Tekin M, Avraham KB, King MC, and Kanaan M. 2006. Genomic Analysis of a Heterogeneous Mendelian Phenotype: Multiple Novel Alleles for Inherited Hearing Loss in the Palestinian Population. Human Genomics 2:203-211.
Walsh T, Walsh V, Vreugde S, Hertzano R, Shahin H, Haika S, Lee MK, Kanaan M, King MC, Avraham KB. 2002. From flies' eyes to our ears: mutations in a human class III myosin cause progressive nonsyndromic hearing loss DFNB30. Proc Natl Acad Sci U S A. 99:7518-23.
Shahin H, Walsh T, Sobe T, Lynch E, King MC, Avraham KB, Kanaan M. 2002. Genetics of congenital deafness in the Palestinian population: multiple connexin 26 alleles with shared origins in the Middle East. Hum Genet 110:284-9.
Young TL, Ives E, Lynch E, Person R, Snook S, MacLaren L, Fernandez B, Lee MK,King MC. 2001. Nonsyndromic progressive hearing loss DFNA38 is caused by heterozygous missense mutation in the Wolfram syndrome gene WFS1. Human Mol Genet 10: 2509-14.
McGuirt WT, Prasad SD, Griffith AJ, Kunst HP, Green GE, Shpargel KB, Runge C, Huybrechts C, Mueller RF, Lynch E, King MC, Brunner HG, Cremers CW, Takanosu M, Li SW, Arita M, Mayne R, Prockop DJ, Van Camp G, Smith RJ. 1999. Mutations in COL11A2 cause non-syndromic hearing loss (DFNA13). Nat Genet. 23:413-9.
Lalwani AK, Jackler RK, Sweetow RW, Lynch ED, Raventos H, Morrow J, King M-C, Leon PE. 1998. Further characterization of the DFNA1 audiovestibular phenotype. Arch Otolaryn Head Neck Surg 124:689-702
Vahava O, Morell R, Lynch ED, Weiss S, Kagan ME, Ahituv N, Morrow JE, Lee MK, Skvorak AB, Morton CC, Blumenfeld A, Frydman M, Friedman TB, King M-C, Avraham KB. 1998. Mutation in transcription factor POU4F3 associated with inherited progressive hearing loss in humans. Science 279:1950-1954.
Lynch ED, Lee MK, Morrow JE, Welcsh, PL, Leon PL, King M-C. 1997. Non-syndromic deafness DFNA1 associated with mutation of a human homolog of the Drosophila gene diaphanous. Science 278:1315-1318.
Leon PE, Raventos H, Lynch E, Morrow J, King MC. 1992. A gene for inherited deafness maps to chromosome 5q31. Proc Natl Acad Sci USA 89:5181-5184.
Schizophrenia & Neurogenetic Disorders
Nord AS, Roeb W, Dickel DE, Walsh T, Kusenda M, O'Connor KL, Malhotra D, McCarthy SE, Stray SM, Taylor SM, Sebat J; STAART Psychopharmacology Network, King B, King MC, McClellan JM. 2011. Reduced transcript expression of genes affected by inherited and de novo CNVs in autism. Eur J Hum Genet. 19(6):727-31. Epub 2011 Mar 30.
Vacic V, McCarthy S, Malhotra D, Murray F, Chou HH, Peoples A, Makarov V, Yoon S, Bhandari A, Corominas R, Iakoucheva LM, Krastoshevsky O, Krause V, Larach-Walters V, Welsh DK, Craig D, Kelsoe JR, Gershon ES, Leal SM, Dell Aquila M, Morris DW, Gill M, Corvin A, Insel PA, McClellan J, King MC, Karayiorgou M, Levy DL, DeLisi LE, Sebat J. 2011. Duplications of the neuropeptide receptor gene VIPR2 confer significant risk for schizophrenia. Nature. ;471(7339):499-503. Epub 2011 Feb 23. Erratum in: Nature. 2011 Jun 2;474(7349):114.
McClellan J, King MC. 2010. Genomic analysis of mental illness: a changing landscape. JAMA. 303:2523-4.
Akil H, Brenner S, Kandel E, Kendler KS, King MC, Scolnick E, Watson JD, Zoghbi HY. 2010. Medicine. The future of psychiatric research: genomes and neural circuits. Science. 327:1580-1.
Girirajan S, Rosenfeld JA, Cooper GM, Antonacci F, Siswara P, Itsara A, Vives L, Walsh T, McCarthy SE, Baker C, Mefford HC, Kidd JM, Browning SR, Browning BL, Dickel DE, Levy DL, Ballif BC, Platky K, Farber DM, Gowans GC, Wetherbee JJ, Asamoah A, Weaver DD, Mark PR, Dickerson J, Garg BP, Ellingwood SA, Smith R, Banks VC, Smith W, McDonald MT, Hoo JJ, French BN, Hudson C, Johnson JP, Ozmore JR, Moeschler JB, Surti U, Escobar LF, El-Khechen D, Gorski JL, Kussmann J, Salbert B, Lacassie Y, Biser A, McDonald-McGinn DM, Zackai EH, Deardorff MA, Shaikh TH, Haan E, Friend KL, Fichera M, Romano C, Gécz J, DeLisi LE, Sebat J, King MC, Shaffer LG, Eichler EE. A recurrent 16p12.1 microdeletion supports a two-hit model for severe developmental delay. Nat Genet. 42:203-9. Epub 2010 Feb 14.
McCarthy SE, Makarov V, Kirov G, Addington AM, McClellan J, Yoon S, Perkins DO, Dickel DE, Kusenda M, Krastoshevsky O, Krause V, Kumar RA, Grozeva D, Malhotra D, Walsh T, Zackai EH, Kaplan P, Ganesh J, Krantz ID, Spinner NB, Roccanova P, Bhandari A, Pavon K, Lakshmi B, Leotta A, Kendall J, Lee YH, Vacic V, Gary S, Iakoucheva LM, Crow TJ, Christian SL, Lieberman JA, Stroup TS, Lehtimäki T, Puura K, Haldeman-Englert C, Pearl J, Goodell M, Willour VL, Derosse P, Steele J, Kassem L, Wolff J, Chitkara N, McMahon FJ, Malhotra AK, Potash JB, Schulze TG, Nöthen MM, Cichon S, Rietschel M, Leibenluft E, Kustanovich V, Lajonchere CM, Sutcliffe JS, Skuse D, Gill M, Gallagher L, Mendell NR; Wellcome Trust Case Control Consortium, Craddock N, Owen MJ, O'Donovan MC, Shaikh TH, Susser E, Delisi LE, Sullivan PF, Deutsch CK, Rapoport J, Levy DL, King MC, Sebat J. 2009. Microduplications of 16p11.2 are associated with schizophrenia. Nat Genet. 41:1223-7. Epub 2009 Oct 25.
McClellan JM, Susser E, King MC, Rietschel M, Riley B, Zammit S. 2008. Forum: The interplay of genes and environment in psychiatric disorders. Curr Opin Psychiatry. 21(4):322-3.
Walsh T, McClellan JM, McCarthy SE, Addington AM, Pierce SB, Cooper GM, Nord AS, Kusenda M, Malhotra D, Bhandari A, Stray SM, Rippey CF, Roccanova P, Makarov V, Lakshmi B, Findling RL, Sikich L, Stromberg T, Merriman B, Gogtay N, Butler P, Eckstrand K, Noory L, Gochman P, Long R, Chen Z, Davis S, Baker C, Eichler EE, Meltzer PS, Nelson SF, Singleton AB, Lee MK, Rapoport JL, King MC, Sebat J. 2008. Rare structural variants disrupt multiple genes in neurodevelopmental pathways in schizophrenia. Science 320(5875):539-43.
DeAngelis CD, Fontanarosa PB, King MC, Pasche B. 2007. Genetics and genomics: a call for papers. Arch Surg. 142(9):822.
Sebat J, Lakshmi B, Malhotra D, Troge J, Lese-Martin C, Walsh T, Yamrom B, Yoon S, Krasnitz A, Kendall J, Leotta A, Pai D, Zhang R, Lee YH, Hicks J, Spence SJ, Lee AT, Puura K, Lehtimaki T, Ledbetter D, Gregersen PK, Bregman J, Sutcliffe JS, Jobanputra V, Chung W, Warburton D, King MC, Skuse D, Geschwind DH, Gilliam TC, Ye K, Wigler M. 2007. Strong association of de novo copy number mutations with autism. Science. 316(5823):445-9.
McClellan JM, Susser E, King MC. 2007. Schizophrenia: a common disease caused by multiple rare alleles. Br J Psychiatry. 190:194-9.
McClellan JM, Susser E, King MC. 2006. Maternal famine, de novo mutations, and schizophrenia. JAMA. 296(5):582-4.
Other phenotypes:
Pierce SB, Spurrell CH, Mandell JB, Lee MK, Zeligson S, Bereman MS, Stray SM, Fokstuen S, Maccoss MJ, Levy-Lahad E, King MC, Motulsky AG. 2011. Garrod's fourth inborn error or metablism solved by the identification of mutations causing pentosuria. Proc Natl Acad Sci U S A. 108(45):18313-7. Epub 2011 Oct 31.
Pierce SB, Chisholm KM, Lynch ED, Lee MK, Walsh T, Opitz JM, Li W, Klevit RE, King MC. 2011. Mutations in mitochondrial histidyl tRNA synthetase HARS2 cause ovarian dysgenesis and sensorineural hearing loss of Perrault syndrome. Proc Natl Acad Sci U S A. 108(16):6543-8. Epub 2011 Apr 4.
Pierce SB, Walsh T, Chisholm KM, Lee MK, Thornton AM, Fiumara A, Opitz JM, Levy-Lahad E, Klevit RE, King MC. 2010. Mutations in the DBP-deficiency protein HSD17B4 cause ovarian dysgenesis, hearing loss, and ataxia of Perrault Syndrome. Am J Hum Genet. 87(2):282-8. Epub 2010 Jul 30.
Tobin DM, Vary JC Jr, Ray JP, Walsh GS, Dunstan SJ, Bang ND, Hagge DA, Khadge S, King MC, Hawn TR, Moens CB, Ramakrishnan L. 2010. The lta4h locus modulates susceptibility to mycobacterial infection in zebrafish and humans. Cell. 140:717-30.
Renbaum P, Kellerman E, Jaron R, Geiger D, Segel R, Lee M, King MC, Levy-Lahad E. 2009. Spinal muscular atrophy with pontocerebellar hypoplasia is caused by a mutation in the VRK1 gene. Am J Hum Genet. 85:281-9. Epub 2009 Jul 30.
Mefford HC, Sharp AJ, Baker C, Itsara A, Jiang Z, Buysse K, Huang S, Maloney VK, Crolla JA, Baralle D, Collins A, Mercer C, Norga K, de Ravel T, Devriendt K, Bongers EM, de Leeuw N, Reardon W, Gimelli S, Bena F, Hennekam RC, Male A, Gaunt L, Clayton-Smith J, Simonic I, Park SM, Mehta SG, Nik-Zainal S, Woods CG, Firth HV, Parkin G, Fichera M, Reitano S, Lo Giudice M, Li KE, Casuga I, Broomer A, Conrad B, Schwerzmann M, Räber L, Gallati S, Striano P, Coppola A, Tolmie JL, Tobias ES, Lilley C, Armengol L, Spysschaert Y, Verloo P, De Coene A, Goossens L, Mortier G, Speleman F, van Binsbergen E, Nelen MR, Hochstenbach R, Poot M, Gallagher L, Gill M, McClellan J, King MC, Regan R, Skinner C, Stevenson RE, Antonarakis SE, Chen C, Estivill X, Menten B, Gimelli G, Gribble S, Schwartz S, Sutcliffe JS, Walsh T, Knight SJ, Sebat J, Romano C, Schwartz CE, Veltman JA, de Vries BB, Vermeesch JR, Barber JC, Willatt L, Tassabehji M, Eichler EE. 2008. Recurrent rearrangements of chromosome 1q21.1 and variable pediatric phenotypes. N Engl J Med. 359(16):1685-99.
Foulkes WD, Thiffault I, Gruber SB, Horwitz M, Hamel N, Lee C, Shia J, Markowitz A, Figer A, Friedman E, Farber D, Greenwood CM, Bonner JD, Nafa K, Walsh T, Marcus V, Tomsho L, Gebert J, Macrae FA, Gaff CL, Paillerets BB, Gregersen PK, Weitzel JN, Gordon PH, MacNamara E, King MC, Hampel H, De La Chapelle A, Boyd J, Offit K, Rennert G, Chong G, Ellis NA. 2002. The founder mutation MSH2*1906G-->C is an important cause of hereditary nonpolyposis colorectal cancer in the Ashkenazi Jewish population. Am J Hum Genet.71:1395-412.
Chen JJ, Mu H, Jiang Y, King MC, Thomson G, Criswell LA. 2002. Clinical usefulness of genetic information for predicting radiographic damage in rheumatoid arthritis. J Rheumatol. 29:2068-73.
Mu H, Chen JJ, Jiang Y, King MC, Thomson G, Criswell LA. 1999. Tumor necrosis factor a microsatellite polymorphism is associated with rheumatoid arthritis severity through an interaction with the HLA-DRB1 shared epitope. Arthritis Rheum. 42:438-42.
Criswell LA, Mu H, Such CL, King M-C. 1998. Inheritance of the shared epitope and long-term outcomes of rheumatoid arthritis among community-based Caucasian females. Genet Epidemiol 15:61-72.
Mu H, King M-C, Criswell LA. 1998. Relative predispositional effects and mode of inheritance of HLA-DRB1 alleles among community-based Caucasian females with rheumatoid arthritis. Genet Epidemiol 15:123-134.
Rousseau CM, Just JJ, Abrams EJ, Casabona J, Stein Z, King M-C. 1997. CCR5del32 in perinatal HIV-1 infection. J Acquir Immune Defic Syndr Hum Retrovirol 16:239-242.
Rousseau C, Abrams E, Lee M, Urbano R, King M-C. 1997. Long terminal repeat and nef gene variants of human immunodeficiency virus type1 in perinatally infected long-term survivors and rapid progressors. AIDS Res Hum Retrovir 13:1611-1623.
Just JJ, Casabona J, Bertran J, Montane C, Fortuny C, Rodrigo C, Mur A, Bosque M, Jovane L, King M-C. 1996. MHC class II genotypes associated with clinical and immunological manifestations of HIV-1 infection among children in Catalonia, Spain. Tissue Antigens 47:313-318.
Mu H, Charmley P, King M-C, Criswell LA. 1996. Synergism between T cell receptor beta gene polymorphism and HLA-DR4 in susceptibility to rheumatoid arthritis. Arthritis Rheumat 39:931-937.
Just JJ, Abrams E, Louie LG, Urbano R, Wara D, Nicholas SW, Stein Z, King M-C. 1995. Influence of host genotype on progression to AIDS among children infected with HIV-1. J Pediatr 127:544-549.
Just J, Louie L, Abrams E, Wara D, Stein Z, King MC. 1992. Genetic risk factors for perinatally acquired HIV-1 infection. Paediat Perinat Epidemiol 6:215-224.
Louie LG, Newman B, King MC. 1991. Influence of host genotype on progression to AIDS among HIV-infected men. J AIDS 4:814-818.
Gilles K, Louie L, Newman B, Crandall J, King MC. 1987. Genetic susceptibility to AIDS: No association with group-specific component. New Engl J Med 317:630-631.
Torfs C, Huey B, Payami H, Malmgren J, Thomson G, King MC. 1984. Inheritance and possible coinheritance of HLA-linked susceptibilities to insulin-dependent diabetes mellitus, autoimmune thyroid diseases, and rheumatoid arthritis. In Histocompatibility Testing 1984, ED Albert et al. (eds), Springer-Verlag, p. 655.
Human rights/human identification:
Owens KN, Harvey-Blankenship M, King MC. 2002. Genomic sequencing in the service of human rights. Int J Epidemiol 31:53-8.
McKusick VA, Ferrara PB, Kazazian HH, King M-C, Lander ES, Lee HC, Lempert RO, Macklin R, Marr TG, Reilly PR, Sensabaugh GF, Weinstein JB. 1992. DNA Technology in Forensic Science. Commission on Life Sciences, National Research Council. National Academy Press, Washington DC.
Ginther C, Issel-Tarver L, King M-C. 1992. Identifying individuals by sequencing mtDNA from teeth. Nature Genet 2:135-138.
Rowell T, King MC. 1991. Tracing Eve. (Letter to the editor) New Scientist p 61.
King MC. 1991. An application of DNA sequencing to a human rights problem. In Molecular Genetic Medicine 1:117-131. T Friedmann, ed., Academic Press.
Orrego C, King MC. 1990. Determination of familial relationships. In PCR Protocols: A Guide to Methods and Applications, M Innis, D Gelfand, J Sninsky, T White (eds). Acad Press, pp. 416-426.
King MC. 1989. Invited editorial: Genetic testing of identity and relationship. Amer J Human Genet 44:179-181.
Orrego C, Wilson AC, King MC. 1988. Identification of maternally-related individuals by amplification and direct sequencing of a highly polymorphic, noncoding region of mitochondrial DNA. Amer J Human Genet 43:A219.
Spinner NR, King MC. 1985. Polymorphisms of mitochondrially-encoded proteins. Amer J Human Genet 38:159-169.
DiLonardo AM, Darlu P, Baur M, Orrego C, King MC. 1984. Human genetics and human rights: Identifying the families of kidnapped children. Amer J Foren Med Path 5:339-347.
Gene structure, diversity, and evolution
Nord AS, Lee M, King MC, Walsh T. 2011. Accurate and exact CNV identification from targeted high-throughput sequence data. BMC Genomics. 12:184.
Puente XS, Velasco G, Gutierrez-Fernandez A, Bertranpetit J, King MC, Lopez-Otin C. 2006. Comparative analysis of cancer genes in the human and chimpanzee genomes. BMC Genomics 7:15 [Epub ahead of print].
Lipovich l, King MC. 2006. Abundant novel transcriptional units and unconventional gene pairs on human chromosome 22. Genome Resarch, 16:45-54. Epub 2005 Dec 12.
The Chimpanzee Sequencing and Analysis Consortium. 2005. Initial sequence of the chimpanzee genome and comparison with the human genome. Nature 437, 69-87.
Lipovich L, King MC. 2003. Novel transcriptional units and unconventional gene pairs in the human genome: toward a sequence-level basis for primate-specific phenotypes? Cold Spring Harb Symp Quant Biol. 68:461-70
MW Feldman, R C Lewontin & M -C King. 2003. Race: a genetic melting-pot. Nature 424:374.
King MC, Motulsky AG. 2002. Human genetics. Mapping human history. Science. 298:2342-3.
Lipovich L, Hughes AL, King MC, Abkowitz JL, Quigley JG. 2002. Genomic structure and evolutionary context of the human feline leukemia virus subgroup C receptor (hFLVCR) gene: evidence for block duplications and de novo gene formation within duplicons of the hFLVCR locus. Gene 286:203-13.
Lipovich L, Lynch ED, Lee MK, King MC. 2001. A novel sodium bicarbonate cotransporter-like gene in an ancient duplicated region: SLC4A9 at 5q31. Genome Biol. 2:RESEARCH0011.
Owens KM and King M-C. 1999. Genomic views of human history. Science 286: 451-453.
Chen JJ, Hollenbach JA, Trachtenberg EA, Just JJ, Carrington M, Ronningen KS, Begovich A, King MC, McWeeney S, Mack SJ, Erlich HA, Thomson G. 1999. Hardy-Weinberg testing for HLA class II (DRB1, DQA1, DQB1, and DPB1) loci in 26 human ethnic groups. Tissue Antigens. 54:533-42.
Cavalli-Sforza LL, Wilson AC, Cantor CR, Cook-Deegan R, King MC. 1991. Call for a worldwide survey of human genetic diversity: A vanishing opportunity for the human genome project. Genomics 11:490-491.
King MC. 1977. The application of molecular evolution to systematics: Rates, regulation, and the role of natural selection. Ann Missouri Bot Garden 66:181-183.
Wilson AC, Bush GL, Case SM, King MC. 1975. Social structuring of mammalian populations and rate of chromosomal evolution. Proc Natl Acad Sci USA 72:5061-5065.
King MC, Wilson AC. 1975. Our close cousin, the chimpanzee. New Scientist 66:16-18.
King MC, Wilson AC. 1975. Evolution at two levels in humans and chimpanzees. Science 188:107-116.
King MC. 1973. Genetic polymorphisms in chimpanzee and human evolution. Doctoral dissertation, University of California, Berkeley.
Wallace DG, King MC, Wilson AC. 1973. Albumin differences among ranid frogs: Taxonomic and phylogenetic implications. Systematic Zool 22:1-13.
Other publications:
Ozçelik T, Kanaan M, Avraham KB, Yannoukakos D, Mégarbané A, Tadmouri GO, Middleton L, Romeo G, King MC, Levy-Lahad E. 2010. Collaborative genomics for human health and cooperation in the Mediterranean region. Nat Genet. 42:641-5.
McClellan J, King MC. 2010. Genetic heterogeneity in human disease. Cell. 141:210-7.
Feng BJ, Huang W, Shugart YY, Lee MK, Zhang F, Xia JC, Wang HY, Huang TB, Jian SW, Huang P, Feng QS, Huang LX, Yu XJ, Li D, Chen LZ, Jia WH, Fang Y, Huang HM, Zhu JL, Liu XM, Zhao Y, Liu WQ, Deng MQ, Hu WH, Wu SX, Mo HY, Hong MF, King MC, Chen Z, Zeng YX. 2002. Genome-wide scan for familial nasopharyngeal carcinoma reveals evidence of linkage to chromosome 4. Nat Genet. 31:395-9.
Ji HP, King MC. 2001. A functional assay for mutations in tumor suppressor genes caused by mismatch repair deficiency. Hum Mol Genet 10:2737-43.
Lee MK, Lynch ED, King M-C. 1998. SeqHelp: a program to analyze molecular sequences utilizing common computational resources. Genome Res 8:306-312.
Rothenberg K, Fuller B, Rothstein M, Duster T, Kahn MJE, Cunningham R, Fine B, Hudson K, King M-C, Murphy P, Swergold G, Collins F. 1997. Genetic information and the workplace: Legislative approaches and policy challenges. Science 275:1755-1757.
Friedlander Y, Austin MA, Newman B, Edwards K, Mayer-Davis EJ, King M-C. 1997. Heritability of longitudinal changes in coronary heart disease risk factors in women twins. Amer J Human Genet 60:1502-1512.
King M-C. 1997. Leaving Kansas...finding genes in 1997. (Editorial) Nature Genet 15:8-10.
Austin MA, Friedlander Y, Newman B, Edwards K, Mayer-Davis EJ, King M-C. 1997. Genetic influences on changes in body mass index: A longitudinal analysis of women twins. Obes Res 5:326-331.
Just JJ, King M-C, Thomson G, Klitz W. 1997. African American HLA class II allele and haplotype diversity. Tissue Antigens 49:547-555.
Chandrasekharappa SC, Friedman L, King SE, Lee YH, Welsch P, Bowcock AM, Weber BL, King MC, Collins FS. 1994. The gene for pancreatic polypeptide (PPY) and the anonymous marker D17S78 are within 45 kb of each other on chromosome 17q21. Genomics 21:458-460.
King M-C. 1993. Sexual orientation and the X. (Editorial) Nature 364:288.
Friedman LS, Lynch ED, King M-C. 1993. Two independent polymorphisms at the 17b-hydroxysteroid dehydrogenase (EDH17B) gene (17q21). Human Molec Genet 2:821.
Zapata BC, Rebolledo A, Atalah E, Newman B, King M-C. 1992. The influence of social and political violence on the risk of pregnancy complications. Amer J Publ Hlth 82:685-690.
King MC. 1992. Allan C. Wilson: In memoriam. Amer J Human Genet 50:234-235.
Lebo RV, Chance PF, Dyck PJ, Redila-Flores MT, Lynch ED, Golbus MS, Bird TD, King MC, Anderson LA, Hall J, Wiegant J, Jiang Z, Dazin PF, Punnett HH, Schonberg SA, Moore K, Shull MM, Gendler S, Hurko O, Lovelace RF, Latov N, Trofatter J, Conneally PM. 1991. Chromosome 1 Charcot-Marie-Tooth disease (CMT1B) locus in the Fcg receptor gene region. Human Genet 88:1-12.
Hall JM, King MC. 1991. PCR detection of an MboI polymorphism in the ERBB2 (HER2; NEU) gene on chromosome 17q11.2-q12. Nucl Acids Res 19:2515.
Shen FM, Lee MK, King MC. 1991. Complex segregation analysis of primary hepatocellular carcinoma in Chinese families: Interaction of inherited susceptibility and hepatitis B viral infection. Amer J Human Genet 49:88-93.
Dracopoli NC et al. 1991. The CEPH consortium linkage map of human chromosome 1. Genomics 9:686-700.
Louie L, King M-C. 1991. A novel approach to establish human lymphoblastoid cell lines: Epstein-Barr virus transformation of cryopreserved cells. Amer J Human Genet 48:637-638.
Nguyen J, Charmley P, Grody WW, Cederbaum SD, King MC, Gatti RA. 1990. Genetic linkage group (ARG1-D6S33-MYB) on chromosome 6q containing the arginase-1 and MYB genes. Cyto Genet Cell Genet 54:95-96.
Friedman GD, Selby JV, Quesenberry CP, Newman B, King MC. 1990. Eye color and hypertension. Medical Hypothesis 33:201-206.
Shen FM, Lee MK, King MC. 1990. Report on Genetic Epidemiology Workshop I, held at Shanghai Medical University, December 24-31, 1988. Genet Epidemiol 7:231-235.
Newman B, Selby JV, Quesenberry CP, King MC, Friedman GD, Fabsitz RR. 1990. Nongenetic influences of obesity on other cardiovascular disease risk factors: An analysis of identical twins. Amer J Publ Hlth 80:675-678.
Huey B, Hall JM, King MC. 1990. A VNTR polymorphism, D1S110, at 1q21-1q31. Nucl Acids Res 18:1928.
Austin MA, King MC, Vranizan KM, Krauss RM. 1989. The atherogenic lipoprotein phenotype (ALP): A proposed genetic marker for coronary heart disease risk. Circulation 82:495-506.
Zuppan PJ, Hall JM, Ponglikitmongkol M, Spielman R, King M-C. 1989. Polymorphisms at the estrogen receptor locus and linkage relationships on chromosome 6q. Cyto Genet Cell Genet 51:1116.
Anderson LA, Hall JM, Lee MK, Lebo RV, King M-C. 1989. Polymorphisms near chromosome 1cen. Cyto Genet Cell Genet 51:951.
Newman B, Lee M, Stillman L, Louie L, Anderson LA, King MC. 1989. Gene mapping of a simulated complex disease. Prog Clin Biol Res 329:171-176.
Selby JV, Newman B, Quesenberry CP, Fabsitz RR, King MC, Meaney FJ. 1989. Evidence of genetic influence on central body fat in middle-aged twins. Human Biol 61: 179-193.
Newman B, Selby J, Lee M, King MC. 1989. Genetic epidemiology of persistent islet cell antibodies among IDDM patients. Genet Epidemiol 6:123-126.
Austin MA, King MC, Vranizan KM, Newman B, Krauss RM. 1988. Inheritance of low density lipoprotein subclass patterns: Results of complex segregation analysis. Amer J Human Genet 43:838-846.
Bowcock AM, Fulton TR, Daneshvar L, Vollrath D, Smith D, King MC, Bowden D, Donis-Keller H, Cavalli-Sforza LL. 1988. Long-range mapping of the cystic fibrosis gene region. In Cellular and Molecular Basis of Cystic Fibrosis, G Mastella, PM Quinton (eds). San Francisco Press, pp 65-72.
Newman B, Selby J, King MC, Slemenda C, Fabsitz R, Friedman G. 1987. Concordance for type II (non-insulin dependent) diabetes mellitus in male twins. Diabetologia 30:763-768.
Zuppan P, Hall J, King MC. 1987. A new polymorphism at the KRAS locus and linkage with known KRAS polymorphisms. Cyto Genet Cell Genet 46:626.
Hall J, Huey B. Morrow J. King MC. 1987. Polymorphism of HLM2 and linkage relationships on chromosome 1p. Cyto Genet Cell Genet 46:626.
Selby JV, Newman B, King MC, Friedman GD. 1987. Environmental and behavioral determinants of fasting plasma glucose in women: A matched co-twin analysis. Amer J Epidemiol 125:979-989.
Austin MA, King MC, Bawol RD, Hulley SR, Friedman GD. 1987. Risk factors for coronary heart disease in adult female twins: Genetic susceptibility and shared environmental influences. Amer J Epidemiol 125:308-318.
Bowcock AM, Crandall J, Danishvar L, Lee GM, Young B, Zunzunegui MV, Crack C, Cavalli-Sforza LL, King MC. 1986. Genetic analysis of cystic fibrosis: Linkage of DNA and classical markers in multiplex families. Amer J Human Genet 39:669-706.
Beaudet A, Bowcock A, Buchwald M, Cavalli-Sforza LL. Farrell M, King MC, Klinger K, Lalouel J-M, Lathrop G, Naylor S, Ott J, Tsui L-C, Wainwright B, Watkins P, White R, Williamson R. 1986. Linkage of cystic fibrosis to two tightly linked DNA markers: Joint report from a collaborative study. Amer J Human Genet 39:681-693.
Bowcock AM, Lee GM, Sanders MF, Cavalli-Sforza LL, King MC. 1986. Linkage analysis of cystic fibrosis with DNA polymorphisms in multiply-affected families. Human Gene Mapping 8:587-588.
Lee GM, Lattanzio D, Crandall J, King MC. 1986. Linkage analysis of cystic fibrosis with classical markers in multiply-affected families. Human Gene Mapping 8:678-679.
Cavalli-Sforza LL, King MC. 1985. Detecting linkage for genetically heterogenous diseases and estimating heterogeneity from linkage data. Amer J Human Genet 38:599-616.
Torfs CP, King MC, Huey B, Malmgren J. Grumet FC. 1985. Genetic interrelationship between insulin-dependent diabetes mellitus, the autoimmune thyroid diseases, and rheumatoid arthritis. Amer J Human Genet 38:170-187.
Zunzunegui MV, King MC, Coria CF, Charlet J. 1985. Male influences on cervical cancer risk. Amer J Epidemiol 123:302-307.
Bertrams J, Baur MP, Clerget-Darpoux F, King MC, Kollmar C, Neugebauer M, Payami H. 1984. Insulin-dependent diabetes mellitus. In Histocompatibility Testing 1984, ED Albert et al. (eds), Springer-Verlag, pp. 348-358.
King MC. 1984. Genetic and epidemiologic approaches to detecting genetic susceptibility to chemical exposures. Banbury Report 16:377-392.
King MC, Lee GT, Spinner NR, Thomson G, Wrensch MR. 1984. Genetic epidemiology. Ann Rev Publ Hlth 5:1-52.
Berberich FR, Berberich MS, King MC, Engleman EG, Grumet FC. 1983. Hodgkin's Disease susceptibility linked to the HLA locus: Classical linkage analysis and a new concordance method. Human Immunol 6:207-217.
Colwell RK, King MC. 1983. Disentangling genetic and cultural influences on human behavior. In Comparing Behavior: Studying Man Studying Animals, Rajecki DW (ed), Erlbaum Associates, pp. 227-249.
Friedman GD, King MC, Klatsky AL, Hulley SB. 1981. Characteristics of smoking-discordant twins. In Advances in Twin Research: Epidemiological ad Clinical Studies, Gedda L, Parisi P, Nance WE (eds) Liss, New York, pp. 17-22.
King MC, Friedman GD, Lattanzio D, Rodgers G. 1980. Diagnosis of twin zygosity by self-assessment and by genetic analysis. Acta Genet Med Gemell: Twin Research 29:121-126.
Gelpi AP, King MC. 1977. New data on glucose-6-phosphate dehydrogenase deficiency in Saudi Arabia. Human Hered 27:285-291
Gelpi AP, King MC. 1976. Screening for abnormal hemoglobins in the Middle East: New data on hemoglobin S and the presence of hemoglobin C in Saudi Arabia. Acta Haematol 66:334-337.
Gelpi AP, King MC. 1976. Duffy blood group and malaria. Science 191:1284.
Gelpi AP, King MC. 1976. Association of Duffy blood groups with the sickle cell trait. Human Genet 32:65-68.
King EB, Barrett D, King MC, Petrakis NL. 1975. Cellular composition of the nipple aspirate specimen of breast fluid. I. The benign cells. Amer J Clin Path 64:728-738.
King MC. 1973. Agriculture (Chapter 2) and Wild Areas: Industrial threats (Chapter 5). In Politics of Land. Fellmeth RC (ed). Grossman, New York pp. 26-144, 220-245.
King MC, Goodman D, Wilson AC. 1972. The biochemical approach to mutation monitoring in man. Proc Sixth Berkeley Symp Math Stat Prob 6:393-399.
