Exploring distinct T-cell priming microenvironments across lymphatic chains. Image courtesy of Michael Conlon, graduate student.
Human HLN
Myeloid structures of the mediastinal lymph node after 3 weeks post Mtb infection (Red = SIRPa, Green = Zbtb46-GFP, Cyan = Fascin1, White = Mtb). Image courtesy of Elya Shamskhou, PhD candidate, who is also a part of the IMPAcTB consortium.
Mtb specific C7 cells (blue) forming a cluster of activation based on pS6 (purple) and Ki67 expression (green)--in mouse lymph node. Image courtesy of Elya Shamskhou, PhD candidate, who is also a part of the IMAcTB consortium.
Mouse skin. Image courtesy of Miranda Lyons-Cohen, PhD.
Lymph nodes show highly structured organization
zoom in on region inside white square from above figure
Histo Cytometry Work Flow
Whole organ microscopy
Investigating immune cell organization in tumors
B and T cells in mice lung granulomas during M. tuberculosis infection. Image courtesy of Ada de la Cruz and Evelyn Cheng.