| Title | Authors | Journal | Date |
|---|---|---|---|
| Nanopore tweezers show fractional-nucleotide translocation in sequence-dependent pausing by RNA polymerase | Ian C. Nova, Jonathan M. Craig, Abhishek Mazumder, Andrew H. Laszlo, Ian M. Derrington, Matthew T. Noakes, Henry Brinkerhoff, Shuya Yang, Hanif Vahedian-Movahed, Lingting Li, Yu Zhang, Jasmine L. Bowman, Jesse R. Huang, Jonathan W. Mount, Richard H. Ebright, Jens H. Gundlach | PNAS | 2024 |
| Nanopores map the acid-base properties of a single site in a single DNA molecule | Drew C. Smith, Christopher A. Thomas, Jonathan M. Craig, Henry Brinkerhoff, Sarah J. Abell, Michaela C. Franzi, Jessica D. Carrasco, Shuichi Hoshika, Steven A. Benner, Jens H. Gundlach, Andrew H. Laszlo | Nucleic Acids Research | 2024 |
| Detection of phosphorylation post-translational modifications along single peptides with nanopores | Ian C. Nova, Justas Ritmejeris, Henry Brinkerhoff, Theo J.R. Koenig, Jens H. Gundlach, Cees Dekker | Nature Biotechnology | 2024 |
| Enzymatic synthesis and nanopore sequencing of 12-letter supernumerary DNA | Hinako Kawabe, Christopher A. Thomas, Shuichi Hoshika, Myong-Jung Kim, Logan Miessner, Nicholas Kaplan, Jonathan M. Craig, Jens H. Gundlach, Andrew H. Laszlo, Steven A. Benner, Jorge A. Marchand | Nature Communications | 2023 |
| Observing inhibition of the SARS-CoV-2 helicase at single-nucleotide resolution | Sinduja K. Marx, Keith J. Mickolajczyk, Jonathan M. Craig, Christopher A. Thomas, Akira M. Pfeffer, Sarah J. Abell, Jessica D. Carrasco, Michaela C. Franzi, Jesse R. Huang, Hwanhee C. Kim, Henry Brinkerhoff, Tarun M. Kapoor, Jens H. Gundlach, Andrew H. Laszlo, | Nucleic Acids Research | 2023 |
| Assessing readability of an 8-letter expanded deoxyribonucleic acid alphabet with nanopores | Christopher A. Thomas, Jonathan M. Craig, Shuich Hoshikia, Henry Brinkerhoff, Jesse R. Huang, Sarah J. Abell, Hwanhee C. Kim, Michaela C. Franzi, Jessica D. Carrasco, Hyo-Joong Kim, Drew C. Smith, Jens H. Gundlach, Steven A. Benner, Andrew H. Laszlo | JACS | 2023 |
| Nanopore tweezers measurements of RecQ conformational changes reveal the energy landscape of helicase motion | Jonathan M. Craig, Maria Mills, Hwanhee C. Kim, Jesse R. Huang, Sarah J. Abell, Jonathan W. Mount, Jens H. Gundlach, Kier C. Neuman, Andrew H. Laszlo | Nucleic Acids Research | 2022 |
| UPF1 mutants with intact ATPase but deficient helicase activities promote efficient nonsense-mediated mRNA decay | Joseph H Chapman, Jonathan M. Craig, Clara D Wang, Jens H. Gundlach, Kier C. Neuman, J Robert Hogg | Nucleic Acids Research | 2022 |
| Sequence-dependent mechanochemcial coupling of helicase translocation and unwinding at single-nucleotide resolution | Andrew H. Laszlo, Jonathan M. Craig, Momcilo Gavrilov, Ramreddy Tippana, Ian C. Nova, Jesse R. Huang, Hwanhee C. Kim, Sarah J. Abell, Mallory deCampos-Stairiker, Jonathan W. Mount, Jasmine L. Bowman, Katherine S. Baker, Hugh Higginbotham, Dmitriy Bobrovnikov, Taekjip Ha, Jens H. Gundlach | PNAS | 2022 |
| Modelling single-molecule kinetics of helicase translocation using high-resolution nanopore tweezers (SPRNT) | Jonathan M. Craig, Andrew H. Laszlo, Ian C. Nova, Jens H. Gundlach | Essays in Biochemistry | 2021 |
| Nanopore Sequencing of an Expanded Genetic Alphabet Reveals High-Fidelity Replication of a Predominantly Hydrophobic Unnatural Base Pair | Michael P. Ledbetter, Jonathan M. Craig, Rebekah J. Karadeema, Matthew T. Noakes, Hwanhee C. Kim, Sarah J. Abell, Jesse R. Huang, Brooke A. Anderson, Ramanarayanan Krishnamurthy, Jens H. Gundlach, Floyd E. Romesberg | JACS | 2020 |
| Increasing the accuracy of nanopore DNA sequencing using a time-varying cross membrane voltage | Matthew T. Noakes, Henry Brinkerhoff, Andrew H. Laszlo, Ian M. Derrington, Kyle W. Langford, Jonathan W. Mount, Jasmine L. Bowman, Katherine S. Baker, Kenji M. Doering, Benjamin I. Tickman, Jens H. Gundlach | Nature Biotechnology | 2019 |
| Determining the effects of DNA sequence on Hel308 helicase translocation along single-stranded DNA using nanopore tweezers | Jonathan M. Craig, Andrew H. Laszlo, Ian C. Nova, Henry Brinkerhoff, Matthew T. Noakes, Katherine S. Baker, Jasmine L. Bowman, Hugh R. Higinbotham, Jonathan W. Mount, Jens H. Gundlach | Nucleic Acids Research | 2019 |
| Investigating asymmetric salt profiles for nanopore DNA sequencing with biological porin MspA | Ian C. Nova, Ian M. Derrington, Jonathan M. Craig, Matthew T. Noakes, Benjamin I. Tickman, Kenji Doering, Hugh Higinbotham, Andrew H. Laszlo, Jens H. Gundlach | PLoS ONE | 2017 |
| Revealing dynamics of helicase translocation on single-stranded DNA using high-resolution nanopore tweezers | Jonathan M. Craig, Andrew H. Laszlo, Henry Brinkerhoff, Ian M. Derrington, Matthew T. Noakes, Ian C. Nova, Benjamin I. Tickman, Kenji Doering, Noah F. de Leeuw, Jens H. Gundlach | PNAS | 2017 |
| MspA nanopore as a single-molecule tool: From sequencing to SPRNT | Andrew H. Laszlo, Ian M. Derrington, Jens H. Gundlach | Methods | 2016 |
| Subangstrom single-molecule measurements of motor proteins using a nanopore | Ian M. Derrington, Jonathan M. Craig, Eric Stava, Andrew H. Laszlo, Brian C. Ross, Henry Brinkerhoff, Ian C. Nova, Kenji Doering, Benjamin I. Tickman, Mostafa Ronaghi, Jeffrey G. Mandell, Kevin L. Gunderson, Jens H. Gundlach | Nature Biotechnology | 2016 |
| Direct Detection of Unnatural DNA Nucleotides dNaM and d5SICS using the MspA Nanopore | Jonathan M. Craig, Andrew H. Laszlo, Ian M. Derrington, Brian C. Ross, Henry Brinkerhoff, Ian C. Nova, Kenji Doering, Benjamin I. Tickman, Mark T. Svet, Jens H. Gundlach | PLoS ONE | 2015 |
| Decoding long nanopore sequencing reads of natural DNA | Andrew H. Laszlo, Ian M. Derrington, Brian C. Ross, Henry Brinkerhoff, Andrew Adey, Ian C. Nova, Jonathan M. Craig, Kyle W. Langford, Jenny Mae Samson, Riza Daza, Kenji Doering, Jay Shendure, Jens H. Gundlach | Nature Biotechnology | 2014 |
| Mutual Information between Discrete and Continuous Data Sets | Brian C. Ross | PLoS ONE | 2014 |
| Detection and mapping of 5-methylcytosine and 5-hydroxymethylcytosine with nanopore MspA | Andrew H. Laszlo, Ian M. Derrington, Henry Brinkerhoff, Kyle W. Langford, Ian C. Nova, Jenny Mae Samson, Joshua J. Barlett, Mikhael Pavlenok, Jens H. Gundlach | PNAS | 2013 |
| MspA nanopores from subunit dimers | Mikhail Pavlenok, Ian M. Derrington, Jens H. Gundlach, Michael Niederweis | PLoS ONE | 2012 |
| Molecular Dynamics Study of MspA Arginine-Mutants Predicts Slow DNA Translocations and Ion current blockades indicative of DNA sequence | Swati Bhattacharya, Ian M. Derrington, Mikhail Pavlenok, Michael Niederweis, Jens H. Gundlach, Aleksei Aksimentiev | ACS Nano | 2012 |
| Reading DNA at single-nucleotide resolution with a mutant MspA nanopore and phi29 DNA polymerase | Elizabeth A. Manrao, Ian M. Derrington, Andrew H. Laszlo, Kyle W. Langford, Matthew K. Hopper, Nathaniel Gillgren, Mikhail Pavlenok, Michael Niederweis, Jens H. Gundlach | Nature Biotechnology | 2012 |
| Nucleotide discrimination with DNA immobilized in the MspA nanopore | Elizabeth A. Manrao, Ian M. Derrington, Mikhail Pavlenok, Michael Niederweis, Jens H. Gundlach | PLoS ONE | 2011 |
| Nanopore DNA sequencing with MspA | Ian M. Derrington, Tom Z. Butler, Marcus D. Collins, Elizabeth Manrao, Mikhail Pavlenok, Michael Niederweis, Jens H. Gundlach | PNAS | 2010 |
| Unsupported planar lipid membranes formed from mycolic acids of Mycobacterium tuberculosis | Kyle W. Langford, Boyan Penkov, Ian M. Derrington, Jens H. Gundlach | Journal of Lipid Research | 2010 |
| Single-molecule DNA detection with an engineered MspA protein nanopore | Tom Z. Butler, Mikhail Pavlenok, Ian M. Derrington, Michael Niederweis, Jens H. Gundlach | Biophysical Journal | 2008 |
| Ionic current blockades from DNA and RNA molecules in the a-Hemolysin nanopore | Tom Z. Butler, Jens H. Gundlach, Mark A. Troll | Biophysical Journal | 2007 |
| Determination of RNA orientation during translocation through a biological nanopore | Tom Z. Butler, Jens H. Gundlach, Mark A. Troll | Biophysical Journal | 2006 |