Using EPR spectroscopy to explore proteins and molecular spin qubits
Developing improved theory, software, and hardware for more detailed and robust data
Analysis and modeling of protein conformational landscapes using site directed spin labeling
Structure and dynamics of biological reactions involving transition metals and organic radicals
Software for simulation and analysis of EPR data
Our principal focus is advanced Electron Paramagnetic Resonance (EPR) spectroscopy, a set of techniques that allows us to measure molecules with unpaired electrons such as organic radicals and transition metal ions and learn about their structure and nano-environment. EPR is similar to NMR spectroscopy, but uses unpaired electrons instead of magnetic nuclei.
Our research program has several areas of activity: (1) structure and function of proteins, (2) quantum science, and (3) EPR methods development.
Using DEER spectroscopy, a type of EPR that measures nanoscale distances between unpaired electrons, we study the structure and dynamics of proteins, in order to understand how they function and how they are regulated.
Using EPR, we study the quantum decoherence dynamics of molecular spin qubits. We develop methods for precise coherent control of these qubits and work on quantum sensing approaches.
We develop new EPR spectroscopy methods, with the goal of improving sensitivity and resolution. For this, we build new instruments, develop new excitation schemes, conceive new data analysis approaches, and devise new quantum simulation methods.
Our research covers areas in physical chemistry, spectroscopy, quantum science, bioinorganic chemistry and biophysics.