MGRC Overview

  • Development of combinatorial and intersectional recombinase strategies for neural circuit dissection
  • Combinatorial CRISPR/SaCas9 strategies for gene inactivation and circuit manipulation
  • Implementation of new sensors and actuators for neural imaging and manipulation
  • Implementation of new packing systems for AAV production

What we do:

  • Provide viral reagents (AAVs) for pilot projects.
  • Generate viral-based CRISPR-SaCas9 reagents and validation for pilot projects.
  • Generate new reagents for neural circuit analysis.
  • Implement new viral-based techniques for circuit analysis.
  • Consultation for molecular genetic approaches to neural circuit dissection.
  • Provide lists of viral vectors available at the NAPE MGRC ( Contact Selena Schattauer (schreibs@uw.edu) or Larry Zweifel (larryz@uw.edu) for requests or further information):

What we do not do:

  • We are not a viral core for large scale production.
  • We do not make virus to order for long-range or large projects.