Calendar

Classes meet Thursdays and Fridays 10:00 - 11:20 am

Q/A and Office Hour with Prof on Thursdays 11:20 - 12:00 pm

Labs meet Fridays 11:30-2:20 pm and lab assignments are due at the beginning of lab

All classes and labs are in person

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Week Date Lecture Lab
1 1/4 L1: Introduction, Housekeeping, and Protein Structure Lab 1:Intro and Homology Modeling with MODELLER (due 1/12 at beginning of lab)
1/5 L2: Homology Modeling and Intro to First Lab
2 1/11 L3: Protein Structure and Rosetta Lab 2: Intuitive Design, Rosetta Design (due 1/19, beginning of lab)
1/12 L4: Structure, Forces and Molecular Mechanics
3 1/18 L5: Molecular Dynamics Lab 3: MD: WT full, RD full, WT fragment, designed fragment (due 1/26, beginning of lab)
1/19 L6: MD and MD Analysis
4 1/25 L7: Rules for Design 1 Lab 4: MD Analysis, Generation II Design and Simulation (due 2/2, beginning of lab)
1/26 L8: Rules for Design 2
5 2/1 L9: Rules for Design 3 Lab 5: Generation II Analysis, Final Writeup (due 2/9, beginning of lab)
2/2 Rosetta, MD and Design
6 2/8 L10: Design Examples 1 Final Lab Writeups Due 2/9 by 11:59 PM
Start Project
2/9 L11: Design Examples 2
7 2/15 Literature Review Work on Project
2/16 Literature Review
8 2/22 Rosetta Design Examples: David Baker Work on Your Project
2/23 L12: Design Examples 3
9 2/29 L13: Design Examples 4 Work really hard on your project
3/1 Sarah Nick : Biosensors
10 3/7 588 Presentations Keep Working Really Hard on Your Project
3/8 588 Presentations
3/14/24 Project Writeups: Writeups due on or before Friday 3/15/24 at 5 pm. Email PDF of your writeup to DAGGETT at uw AND to SNICK36 at uw