Vallur AC, Maizels N. 2010. Distinct activities of exonuclease 1 and flap endonuclease 1 at telomeric g4 DNA. PLoS One. 2010 Jan 26;5(1):e8908.
Ordinario EC, Yabuki M, Handa P, Cummings WJ, Maizels N. 2009. RAD51 paralogs promote homology-directed repair at diversifying immunoglobulin V regions. BMC Mol Biol. 2009 Oct 28;10:98.
Ordinario EC, Yabuki M, Larson RP, Maizels N. 2009. Temporal regulation of Ig gene diversification revealed by single-cell imaging. J Immunol. 2009 Oct 1;183(7):4545-53. Epub 2009 Sep 11.
Eddy J, Maizels N. 2009. Selection for the G4 DNA motif at the 5' end of human genes. Mol Carcinog. 2009 Apr;48(4):319-25.
McConnell Smith A, Takeuchi R, Pellenz S, Davis L, Maizels N, Monnat RJ Jr, Stoddard BL. 2009. Generation of a nicking enzyme that stimulates site-specific gene conversion from the I-AniI LAGLIDADG homing endonuclease. Proc. Natl. Acad. Sci. 2009 Mar 31
Yabuki M, Ordinario EC, Cummings WJ, Fujii MM, Maizels N.2009 E2A acts in cis in G1 phase of cell cycle to promote Ig gene diversification. J Immunol. 2009 Jan 1;182(1):408-15.
Cummings WJ, Bednarski DW, Maizels N. 2008. Genetic variation stimulated by epigenetic modification. PLoS One. 2008;3(12):e4075. Epub 2008 Dec 30.
Larson ED, Bednarski DW, Maizels N. 2008. High-fidelity correction of genomic uracil by human mismatch repair activities. BMC Mol Biol. 2008 Oct 27;9:94.
Vallur AC, Maizels N. 2008. Activities of human exonuclease 1 that promote cleavage of transcribed immunoglobulin switch regions. Proc. Natl. Acad. Sci. 2008 Oct 28
Maizels N. 2008. Genomic stability: FANCJ-dependent G4 DNA repair. Curr Biol. 2008 Jul 22
Eddy, J. and Maizels, N. 2008. Conserved elements with potential to form polymorphic G-quadruplex structures in the first intron of human genes. Nucleic Acids Res. epub 1/10/08.
Cummings W.J., Yabuki M., Ordinario E.O., Bednarski D.W., Quay S., and Maizels N. 2007. Chromatin Structure Regulates Gene Conversion. PLoS Bio. 18;5(10):e246.
Duquette, M.L., Huber, M.D., Maizels, N. 2007. G-rich proto-oncogenes are targeted for genomic instability in B-cell lymphomas. Cancer Res. 67(6): 2586-2594.
Vallur, A.C.., Yabuki, M., Larson, E.D., Maizels, N. 2007. AID in antibody perfection. Cell. Mol. Life Sci. 64(5): 555-565.
Maizels, N. 2006. Dynamic roles for G4 DNA in the biology of eukaryotic cells. Nat. Struct. Mol. Biol. 13: 1055-1059.
Maizels, N. 2006. Quadruplexes and the biology of G-rich genomic regions. In Quadruplex Nucleic Acids, S. Neidle and S. Balasubramanian, eds. Royal Society of Chemistry/Springer, Cambridge, UK, pp. 228-252.
Eddy, J., Maizels, N. 2006. Gene function correlates with potential for G4 DNA formation in the human genome. Nucleic Acids Res. 34(14): 3887-3896.
Huber, M.D., Duquette, M.L., Shiels, J.C., Maizels, N. 2006. A conserved G4 DNA binding domain in RecQ family helicases. J Mol Biol.358: 1071-80.
Maizels, N. 2006. Regulated and unregulated recombination at G-rich genomic regions. In The Implicit Genome, L.H. Caporale, ed. Oxford University Press, Oxford, UK, pp. 191-207.
Larson, E.D., Cummings, W.J., Bednarski, D.W., Maizels, N. 2005. MRE11/RAD50 cleaves DNA in the AID/UNG-dependent pathway of immunoglobulin gene diversification. Molecular Cell. 20: 367-375.
Yabuki, M., Fujii, M., Maizels, N. 2005. The MRE11/RAD50/NBS1 complex accelerates somatic hypermutation and gene conversion of immunoglobulin genes. Nature Immunol. 6: 730-736.
Duquette, M.L., Pham, P., Goodman, M.F. and Maizels, N. 2005. AID binds to transcription-induced structures in c-MYC that map to regions associated with translocation and hypermutation. Oncogene. 24: 5791-5798.
Larson, E.D., Duquette, M.L., Cummings, W.J., Streiff, R.J. and Maizels, N. 2005. MutSα binds to and promotes synapsis of transcriptionally activated immunoglobulin switch regions. Curr. Biol. 15: 470-474.
Maizels, N. 2005. Immunoglobulin gene diversification. Annu. Rev. Genetics. 39: 23-46.
Duquette, M.L., Handa, P., Vincent, J., Taylor, A.F., and Maizels, N. 2004. Intracellular transcription of G-rich DNAs induces formation of G-loops, novel structures containing G4 DNA. Genes Dev. 18: 1618-1629.
Larson, E.D. and Maizels, N. 2004. Transcription-coupled mutagenesis by the DNA deaminase AID. Genome Biol. 5: 211-213.
Maizels, N. and Scharff, M.D. 2003. Molecular mechanisms of hypermutation. In Molecular Biology of B Cells, M. Neuberger, T. Honjo and F.W. Alt, eds. Academic Press, New York, pp. 327-338.
Cocco, M.D., Hanakahi, L.A., Huber, M.D. and Maizels, N. 2003. Specific interactions of distamycin with G quadruplex DNA. Nucleic Acids Res . 31: 2944-2951.
Maizels, N. 2003. Yin outwits Yang at the IgE locus. Nature Immunol. 4: 7-8.
Huber, M.D., Lee, D.C. and Maizels, N. 2002. G4 DNA unwinding by BLM and Sgs1p: substrate-specificity and substrate-specific inhibition. Nucleic Acids Res. 30: 3954-3961.
Sun, H., Yabuki, A. and Maizels, N. 2001. A human nuclease specific for G4 DNA. Proc. Natl. Acad. Sci. USA. 98: 12444-12449.
Maizels, N. 2001. Recombination in the immune system. In Encyclopedia of Genetics, J.H. Miller and S. Brenner, eds. Academic Press, New York, NY, pp. 1640-1642.
Kong, Q. and Maizels, N. 2001. DNA breaks in hypermutating immunoglobulin genes: evidence for a break and repair pathway of somatic hypermutation. Genetics 158: 369-378.
Kong, Q. and Maizels, N. 2001. Breaksite batch mapping, a rapid method for assay and identification of DNA breaksites in mammalian cells. Nucleic Acids Res. 29: e33.
Wu, X. and Maizels, N. 2001. Substrate-specific inhibition of RecQ helicase. Nucleic Acids Res. 29: 1765-1771.
Hanakahi, L.A., Bu, Z. and Maizels, N. 2000. The C-terminal domain of nucleolin accelerates nucleic acid annealing. Biochemistry 39:15493-15499.
Maizels, N. 2000. Secret sharers in the immune system: a novel RNA editing activity links switch recombination and somatic hypermutation(minireview). Genome Biology 1:1025.1-1025.3.
Eversole, A. and Maizels, N. 2000. In Vitro Properties of the Conserved Mammalian Protein hnRNP D Suggest a Role in Telomere Maintenance. Mol. Cell. Biol. 20:5425-5432.
Hanakahi, L.A. and Maizels, N. 2000. Transcriptional activation by LR1 at the Eµ enhancer and switch region sites. Nucleic Acids Res. 28:2651-2657.
Liu, Y. and Maizels, N. 2000. Coordinated response of mammalian Rad51 and Rad52 to DNA damage. EMBO Reports 1:85-90.
Gallouzi, I.-E., Brennan, C.M., Stenberg, M.G., Swanson, M.S., Eversole, A., Maizels, N. and Steitz, J.A. 2000. HuR binding to cytoplasmic mRNA is perturbed by heat shock. Proc. Natl. Acad. Sci . USA 97:3073-3078.
Li, M.-J. and Maizels, N. 1999. Activation and targeting of immunoglobulin switch recombination by activities induced by Epstein–Barr virus infection. 1999. J. Immunol. 163: 6659– 6664.
Liu, Y., Li, M.-J., Lee, E. Y.-H. P. and Maizels, N. 1999. Localization and dynamic relocalization of mammalian Rad52 during the cell cycle and in response to DNA damage. Curr. Biol. 9:975-978.
Kong, Q. and Maizels, N. 1999. Hypermutation of a l1 transgene is diminished in young but not old Pms2-deficient mice. Mol. Immunol. 36:83-91.
Hanakahi, L.A., Sun, H. and Maizels, N. 1999. High affinity interactions of nucleolin with G-G paired rDNA. J. Biol. Chem . 274:15908-15912.
Sun, H., Bennett, R. J. and Maizels, N. 1999. The S. cerevisiae Sgs1 helicase efficiently unwinds G-G paired DNAs. Nucleic Acids Res. 27: 1978-1984.
Weiner, A.M. and Maizels, N. 1999. A deadly double life. Science 284:63-64.
Maizels, N., Weiner, A.M., Yue, D. and Shi, P.-Y. 1999. New evidence for the genomic tag hypothesis: archaeal CCA-adding enzymes and tDNA substrates. Biol. Bull. 196:331-334.
Weiner, A.M. and Maizels, N. 1999. The genomic tag hypothesis: modern viruses as molecular fossils of ancient strategies for genomic replication, and clues regarding the origin of protein synthesis. Biol. Bull. 196:327-330.
Maizels, N. 1999. Immunoglobulin class switch recombination: will genetics provide new clues to mechanism? Am. J. Hum. Genet . 64:1270-1275.
Harris, R.S., Kong, Q. and Maizels, N. 1999. Somatic hypermutation and the three R's: repair, replication and recombination. Rev. Mutat. Res. 436:157-178.
Maizels, N. and Weiner, A.M. 1999. The genomic tag hypothesis: what molecular fossils tell us about the evolution of tRNA. In The RNA World, second edition. R.F. Gesteland and J.F. Atkins, eds. Cold Spring Harbor Press, Cold Spring Harbor, New York, pp. 79-111.
Dempsey, L.A., Sun, H., Hanakahi, L.A. and Maizels, N. 1999. G4 DNA binding by LR1 and its subunits, nucleolin and hnRNP D: a role for G-G pairing in immunoglobulin switch recombination. J. Biol. Chem . 274:1066-1071.
Yue, D., Weiner, A.M. and Maizels, N. 1998. The CCA-adding enzyme has a single active site. J. Biol. Chem . 273:29693-29700.
Dempsey, L.A., Hanakahi, L.A. and Maizels, N. 1998. A specific isoform of hnRNP D interacts with DNA in the LR1 heterodimer: canonical RNA binding motifs in a sequence-specific duplex DNA binding protein. J. Biol. Chem . 273:29224-29229.
Sun, H., Karow, J.K., Hickson, I.D. and Maizels, N. 1998. The Bloom’s syndrome helicase unwinds G4 DNA. J. Biol. Chem. 273: 27587-27592.
Peakman, M.-C. and Maizels, N. 1998. Localization of splenic B cells activated for switch recombination by in situ hybridization with Ig1 switch transcript and Rad51 probes. J. Immunol . 161:4008-4015.
Kong, Q., Zhao, L, Subbaiah, S. and Maizels, N. 1998. A l 3’ enhancer drives active and untemplated somatic hypermutation of a l1 transgene. J. Immunol. 161:294-301.
Dempsey, L.A., Li, M.-J., DePace, A., Bray-Ward, P. and Maizels, N. 1998. The human HNRPD locus maps to 4q21 and encodes a highly conserved protein. Genomics 49:378-384.
Kong, Q., Harris, R. S. and Maizels, N. 1998. Recombination-based mechanisms for somatic hypermutation. Immunol. Rev. 162:67-76.
Shi, P.-Y., Maizels, N. and Weiner, A.M. 1998. CCA addition by tRNA nucleotidyltransferase: polymerization without translocation? EMBO J . 17:3197-3206.
Shi, P.-Y., Weiner, A.M. and Maizels, N. 1998. A top-half tDNA minihelix is a good substrate for the eubacterial CCA-adding enzyme. RNA 4:276-284.
Ashburner, M. and Maizels, N. 1997. Post-genome, pre-chromosome. Curr. Opinion Genet. and Devel. 7:747-749.
Shi, P.-Y., Maizels, N. and Weiner, A.M. 1997. Recovery of soluble, active recombinant protein from inclusion bodies. BioTechniques 23:1036-1038.
Li, M.-J. and Maizels, N. 1997. Nuclear Rad51 foci induced by DNA damage are distinct from Rad51 foci associated with B cell activation and recombination. Exp. Cell Res. 237:93-100.
Hanakahi, L.A., Dempsey, L.A., Li, M.-J. and Maizels, N. 1997. Nucleolin is one component of the B cell-specific transcription factor and switch region binding protein, LR1. Proc. Natl. Acad. Sci. USA 94:3605-3610.
Yue, D., Maizels, N. and Weiner, A.M. 1996. CCA-adding enzymes and poly(A) polymerases are all members of the same nucleotidyltransferase superfamily: Characterization of the CCA-adding enzyme from the archæal hyperthermophile Sulfolobus shibatae. RNA 2:895-908.
Li, M.-J., Peakman, M.-C., Golub, E.I., Reddy, G., Ward, D.C., Radding, C.M. and Maizels, N. 1996. Rad51 expression and localization in B cells carrying out class switch recombination. Proc. Natl. Acad. Sci. USA 93:10222-10227.
Maizels, N. 1995. Somatic hypermutation: How many mechanisms diversify V region sequences? Cell 83:9-12.
Bulfone-Paus, S.B., Dempsey, L.A. and Maizels, N. 1995. Host factors LR1 and Sp1 regulate the Fp latent promoter of Epstein-Barr virus. Proc. Natl. Acad. Sci. USA 92:8293-8297.
Hengstschläger, M. and Maizels, N. 1995. Isotype exclusion in l1 transgenic mice depends on transgene copy number and diminishes with downregulation of transgene transcripts. Eur. J. Immunol. 25:187-191.
Hengstschläger, M., Maizels, N. and Leung, H. 1995. Targeting and regulation of immunoglobulin gene somatic hypermutation and isotype switch recombination. Progress in Nucleic Acids Res. and Mol. Biol. 50:67-99.
Maizels, N. and Weiner, A. M. 1994. Phylogeny from function: evidence from the molecular fossil record that tRNA originated in replication, not translation. Proc. Natl. Acad. Sci. USA 91:6729-6734.
Hengstschläger, M., Williams, M. and Maizels, N. 1994. A l1 transgene under the control of the heavy chain promoter and enhancer does not undergo somatic hypermutation. Eur. J. Immunol. 24:1649-1656.
Weiner, A.M. and Maizels, N. 1994. Unlocking the secrets of retroviral evolution. Current Biol. 6:560-563.
Brys, A. and Maizels, N. 1994. LR1 regulates c-myc transcription in B cell lymphomas. Proc. Natl. Acad. Sci. USA 91:4915-4919.