ME567/ME498/MOLENG 567: Micro- and Nanostructured Biosensors
Objectives: This course will focus on chemical- and biosensors using micromachining and nanotechnology. The working principles of the sensors are addressed with the fabrication process, system integration and performance evaluation. The demands and challenges for current chemical- and biosensors are introduced. The innovative concepts and fabrication approaches are delivered to address the challenges. The pros and cons of the nanoscale sensors are explained with next generation platforms, such as wearable devices and remote sensors. Through the course, students will be able to classify biochemical sensors, analyze the sensor systems, design the fabrication process and identify the evaluation methods of the sensors.

Topics: Introduction to biochemical sensors, sensor integration, performance evaluation, signal processing, fabrication process, SPR sensors, glucose sensors, immunoassay, genotyping, PCR, DNA preparation, microarray, DNA chips, electrochemical sensors, fluorescence detection, point-of-care devices, etc.

Course Requirements and Grading: Students will review papers related to nanotechnology, design a fabrication process for a sensor, and write a term paper with presentations. Two exams will be given in the course.

Text book: Journal papers including review papers and reading material will be provided by the instructor.

ME410-Nano-Devices: Design and Manufacture
Objectives: This course will focus on designing, fabricating, and manufacturing nanodevices with state-of-the-art nanotechnology. Current nanomanufacturing methods are introduced in conjunction with micromachining technology in order to create innovative nanodevices. Through the course, students will be able to classify nanoscale materials and nanomanufacturing methods, choose appropriate fabrication processes, and furthermore design nanodevices.

Topics: Introduction to nanotechnology, microscopes, nanomaterials (including synthesis and growth), top-down manufacturing processes (micromachining and nanoscale patterning methods), bottom-up manufacturing processes (self-assembly, and e-field, fluid flow, and magnetic field induced assembly), softlithography, nanodevices and applications. Three experiments using carbon nanotubes are planned to fabricate and test a tactile sensor, a gas sensor and an Al-oxygen battery.

Text book: Reading material will be provided by the instructor.