The Zheng Laboratory

Structural Biology - Life Sciences at the Atomic Resolution

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Earlier publications

Rubin SM, Gall AL, Zheng N, and Pavletich NP 2005. Structure of the Rb C-terminal Domain Bound to an E2F1-DP1 Heterodimer: A Mechanism for Phosphorylation-Induced E2F Release.
Cell 123:1093-1106.

Hao B, Zheng N, Schulman BA, Wu G, Pagano M, and Pavletich NP 2005. Structural basis of the Cks1-dependent recognition of p27Kip1 by the SCFSkp2 ubiquitin ligase. 
Mol Cell 20:9-19.

Yang H, Jeffrey PD, Miller JJ, Kinnucan E, Sun Y, Thoma N. Zheng N, Chen P, Lee WH, Pavletich  NP. 2002. BRCA2 Function in DNA Binding and Recombination from a BRCA2-DSS1-ssDNA Structure.
Science 297: 1837-1848 (Cover Story).

Zheng N
& Pavletich NP 2004.  Structural Biology of the Cullin-Based Ubiquitin Ligases. Ed. John Meyer. Protein Degradation. Vol 1. Ubiquitin and the Chemistry of Life. Wiley VCH

Zheng N
, Schulman B, Miller JJ, Wang P, Jeffrey PD, Chu C, Koepp DM, Elledge SD, Pagano N, Conaway RC, Conaway JW, Harper JW and Pavletich NP. 2002. Structure of the Cul1-Rbx1-Skp1-FboxSkp2 Ubiquitin-Protein Ligase Complex. Nature 416: 703-709 (Cover story).

Zheng N
, Wang P, Jeffrey PD and Pavletich NP. 2000. Structure of a c-Cbl-UbcH7 Complex: RING Domain Function in Ubiquitin-Protein Ligases.  Cell 102: 533-539.

Zheng N
, Fraenkel E, Pabo CO and Pavletich NP 1999. Structural Basis of DNA Recognition by the Heterdimeric Cell Cycle Transcription Factor E2F-DP.  Genes & Dev 13 (6): 666-674 (Cover story).

Zheng N
& Gierasch LM 1997. Domain Interactions in E. coli SRP: Stabilization of the M Domain by RNA Binding Is Required for Effective Signal Sequence Modulation of the NG Domain.  Mol Cell 1: 79-87.

Cleverley RM, Zheng N, and Gierasch LM 2001. The Cost of Exposing a Hydrophobic Loop and Implication for the Functional Role of 4.5S RNA in the E. coli SRP. 
J Biol Chem (276):19327-19331.

Zheng N
& Gierasch LM 1996.  Signal Sequences: the Same yet Different. (Minireview) Cell 86: 849-852.