UW Human Photonics Lab

Millifluidic Biospecimen Prep

Pathology in a Tube for 3D optical imaging

Prototype milli-fluidic device for staining a fresh core needle biopsy.

Das, R., Kramer, G.M., Burfeind, C.W., and Seibel, E.J. (2014) Pathology in a tube, step 1: fixing, staining, and transporting pancreatic core biopsies in a microfluidic device for 3D imaging, Microfluidics, BioMEMS, and Medical Microsystems XII, Proc. SPIE vol. 8976, paper 89760R-1-8.

Das, R., Burfeind, CW, Lim, SD, Patle, S., Seibel, EJ. (2018) Pathology in a tube: Step 2. Simple, rapid fabrication of curved, circular cross section millifluidic channels for biopsy preparation/3D imaging towards pancreatic cancer diagnosis, Proc. SPIE 10491, Microfluidics, BioMEMS, and Medical Microsystems XVI, 1049118 (19 February 2018); doi:10.1117/12.2291018.

CoreView – Core Needle Biopsy Assessment

Schematic and photo sequence illustrating biopsy removal process using milli-fluidics.
Milli-fluidic 3D printed device with 14G core needle biopsy
needle inserted and red dye added for visualization.

Cooper, DJ, Fauver, ME, Dintzis, SM, and Seibel, EJ. (2020) Rapid Needle Biopsy Assessment at Point of Care  to Advance Personalized Cancer Therapy, AACR Annual Meeting 2020, virtual presentation, June virtual presentation.