Lipidomic consequences of phospholipid synthesis defects in Escherichia coli revealed by HILIC-ion mobility-mass spectrometry. Kelly M. Hines, Libin Xu. Chem. Phys. Lipids 2019, 219, 15-22. (Link)
Continue reading “Lipidomic consequences of phospholipid synthesis defects in Escherichia coli revealed by HILIC-ion mobility-mass spectrometry”
Principles of Ion Selection, Alignment, and Focusing in Tandem Ion Mobility Implemented Using Structures for Lossless Ion Manipulations (SLIM). Rachel M. Eaton, Samuel J. Allen, Matthew F. Bush. J. Am. Soc. Mass Spectrom. 2019, 30, 1115–1125. (Link)
Continue reading “Principles of Ion Selection, Alignment, and Focusing in Tandem Ion Mobility”
Effects of Charge State on the Structures of Serum Albumin Ions in the Gas Phase: Insights from Cation-to-Anion Proton-Transfer Reactions, Ion Mobility, and Mass Spectrometry. Meagan M. Gadzuk-Shea, Matthew F. Bush. J. Phys. Chem. B 2018, 122, 9947–9955. (Link)
Ion Mobility of Proteins in Nitrogen Gas: Effects of Charge State, Charge Distribution, and Structure. Daniele Canzani, Kenneth J. Laszlo, Matthew F. Bush. J. Phys. Chem. A 2018, 122, 5625−5634. (Link)
Continue reading “Ion Mobility of Proteins in Nitrogen Gas: Effects of Charge State, Charge Distribution, and Structure”
Characterization of the Mechanisms of Daptomycin Resistance among Gram-Positive Bacterial Pathogens by Multidimensional Lipidomics. Kelly M. Hines, Adam Waalkes, Kelsi Penewit, Elizabeth A. Holmes, Stephen J. Salipante, Brian J. Werth, Libin Xu. mSphere 2017, 2, DOI: 10.1128/mSphere.00492-17. (Link)
Previous work suggests that altered lipid metabolism may be associated with daptomycin resistance in Gram-positive pathogens, but lipidomic changes underlying resistance are not fully understood. We performed untargeted lipidomics by using three-dimensional hydrophilic interaction liquid chromatography-ion mobility-mass spectrometry (HILIC-IM-MS) to characterize alterations in the lipidomes of daptomycin-susceptible and -resistant isogenic strain pairs of Enterococcus faecalis, Staphylococcus aureus, and Corynebacterium striatum. Continue reading “Characterization of the Mechanisms of Daptomycin Resistance among Gram-Positive Bacterial Pathogens by Multidimensional Lipidomics”
Effects of Charge State, Charge Distribution, and Structure on the Ion Mobility of Protein Ions in Helium Gas: Results from Trajectory Method Calculations. Kenneth J. Laszlo, Matthew F. Bush. J. Phys. Chem. A, 2017, 121, 7768–7777. (Link)
Large-scale Structural Characterization of Drug and Drug-Like Compounds by High-Throughput Ion Mobility-Mass Spectrometry. Kelly M. Hines, Dylan Ross, Kimberly L. Davidson, Matthew F. Bush, Libin Xu. Anal. Chem. 2017, 89, 9023–9030. (Link)
Effects of Drift Gas Selection on the Ambient-Temperature, Ion Mobility Mass Spectrometry Analysis of Amino Acids. Kimberly L. Davidson and Matthew F. Bush. Anal. Chem. 2017, 89, 2017–2023. (Link)
