Protein interactions with surfaces: Computational approaches and repellency

Citation

Szott, Luisa Mayorga & Horbett, Thomas A. (2011). Protein interactions with surfaces: Computational approaches and repellency. Current opinion in chemical biology, 15(5), 683-689.

Abstract

Study of protein adsorption to solid surfaces continues to be substantial because of its role in cellular responses to biomaterials, interest in molecular aspects such as conformation and orientation, new methods for making protein repellent surfaces, and new application areas such as nanoparticles and microfluidics. This brief review is based only on very recent articles of particular interest to the authors, who each have worked in this area for some time. Simulations of protein interactions with surfaces and protein repellent surfaces are the only subtopics reviewed here.

Keyword(s)

Adsorption
Biocompatible Materials
Humans
Hydrophobic and Hydrophilic Interactions
Methacrylates
Molecular Dynamics Simulation
Monte Carlo Method
Nanotechnology
Polyethylene Glycols
Protein Conformation
proteins
Surface Properties
Thermodynamics

Reference Type

Journal Article

Secondary Title

Current opinion in chemical biology

Author(s)

Szott, Luisa Mayorga
Horbett, Thomas A.

Year Published

2011

Volume Number

Issue Number

Pages

683-689

ISSN/ISBN

1879-0402

DOI

Protein interactions with surfaces10.1016/j.cbpa.2011.04.016