Alliance for Pandemic Preparedness

January 29, 2020

Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study

Category:

Topic:

  • All 99 cases identified from Jan 1 – Jan 20, 2020 at a single Wuhan hospital confirmed by RT-PCR are described. Patients who died aligned with the MuLBSTA score for predicting mortality in viral pneumonia. 
    • 49% had exposure to the Huanan seafood market
    • 51% had chronic diseases 
    • Clinical manifestations: fever (83%), cough (82%), shortness of breath (31%), muscle ache (11%) and confusion, headache, sore throat, rhinorrhea, chest pain, diarrhea, and nausea/vomiting all less than 10%. 
    • 75% had bilateral pneumonia, 14% had multiple mottling and ground glass opacity, one patient had pneumothorax. 
    • 17 patients (17%) developed acute respiratory distress syndrome. 
      • 11 of these died of multiple organ failure.

Chen et al. (Jan 29, 2020). Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. The Lancet. https://marlin-prod.literatumonline.com/pb-assets/Lancet/pdfs/S0140673620302117.pdf