February 13, 2020

ACE2 Expression in Kidney and Testis May Cause Kidney and Testis Damage After 2019 2019-nCoV Infection

Category: Article Summary

Topic: Clinical Characteristics and Health Care Setting

• Clinical data from three previous studies on COVID-19 patients were reviewed for reports of abnormal renal function or kidney damage. Around 10% of patients had abnormal renal function. The 2019-nCoV virus is known to bind to ACE2 cell receptors, and researchers have determined previously that ACE2 cell receptor expression is relatively higher in kidney cells and the testes than other human tissues
• The authors call for follow up and evaluation of reproductive functions among young male patients post recovery. 

Fan et al. (Feb 13, 2020). ACE2 Expression in Kidney and Testis May Cause Kidney and Testis Damage After 2019 2019-nCoV Infection. Pre-print downloaded Feb 13 from https://www.medrxiv.org/content/10.1101/2020.02.12.20022418v1