February 13, 2020

Clinical diagnosis of 8274 samples with 2019-novel coronavirus in Wuhan

Category: Article Summary

Topic: Clinical Characteristics and Health Care Setting

• Researchers evaluate 8,274 people with Wuhan close contacts who were tested for 2019-nCoV, of whom 33.2% had been infected. For 3% of cases (232) diagnosis was not definitive (only one target gene was positive out of two). The results of secondary testing are described along with recommendations for how to handle cases who test positive for only one target gene.
• 104 COVID-19 cases had multiple respiratory infections. 
• Authors emphasize the need for a test that can screen for multiple pathogens simultaneously along with sample pre-processing considerations.

Wang et al. (Feb 13, 2020). Clinical diagnosis of 8274 samples with 2019-novel coronavirus in Wuhan. Pre-print downloaded Feb 13 from https://www.medrxiv.org/content/10.1101/2020.02.12.20022327v1