February 19, 2020

Longitudinal characteristics of lymphocyte responses and cytokine profiles in the peripheral blood of SARS-CoV-2 infected patients

Category: Article Summary

Topic: Clinical Characteristics and Health Care Setting

• Peripheral blood samples were collected longitudinally from 40 confirmed COVID-19 cases and evaluated for lymphocyte subsets and cytokine profiles. Severe cases had more sustained lymphocyte depletion but increased neutrophil counts compared to mild cases. T cell counts were also decreased among severe cases. The neutrophil-to-CD8+ T cell ratio may be a useful prognostic tool for early identification of severe COVID-19 cases.

Liu et al. (Feb 18, 2020). Longitudinal characteristics of lymphocyte responses and cytokine profiles in the peripheral blood of SARS-CoV-2 infected patients. Pre-print downloaded Feb 19 from https://doi.org/10.1101/2020.02.16.20023671