February 28, 2020

Development and Clinical Application of A Rapid IgM-IgG Combined Antibody Test for SARS-CoV-2 Infection Diagnosis. Journal of Medical Virology

Category: Article Summary

Topic: Clinical Characteristics and Health Care Setting

• Li et al developed a rapid and simple point-of-care lateral flow immunoassay to simultaneously detect IgM and IgG antibodies within 15 minutes from human blood, plasma, or serum collected at different stages of infection. Overall sensitivity of the combined test was 88.7% and specificity was 90.6% and had better utility and sensitivity than separate IgM or IgG tests. This new test is potentially applicable for rapid screening of SARS-CoV-2 carriers, symptomatic or asymptomatic, in hospitals, clinics, and test laboratories.

Li et al. (Feb 27, 2020). Development and Clinical Application of A Rapid IgM-IgG Combined Antibody Test for SARS-CoV-2 Infection Diagnosis. Journal of Medical Virology. Pre-print downloaded Feb 28 from https://doi.org/10.1002/jmv.25727