Alliance for Pandemic Preparedness
March 24, 2020
SARS-CoV-2: virus dynamics and host response
Category: Article Summary
Topic: Transmission
- A cohort study analyzing the viral load and antibody profiles of 23 hospitalized patients with COVID-19 presents important findings: (1) the high viral load during the early phase of illness suggests that patients could be most infectious during this period, (2) the potential for antiviral resistance of SARS-CoV-2, (3) high viral loads in elderly patients could explain the high degree of disease severity.
Chen and Li (Mar 23, 2020). SARS-CoV-2: virus dynamics and host response. Lancet Infectious Diseases. https://doi.org/10.1016/S1473-3099(20)30235-8