Alliance for Pandemic Preparedness

April 9, 2020

LAMP-Seq: Population-Scale COVID-19 Diagnostics Using a Compressed Barcode Space

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  • Schmid et al propose using LAMP-Seq, a barcoded Reverse-Transcription Loop-mediated Isothermal Amplification (RT-LAMP) protocol that could dramatically reduce the cost and complexity of population-scale testing of COVID-19. Given the low cost and scalability of next-generation sequencing, the team believes that this method could be affordably scaled to analyze millions of samples per day using existing sequencing infrastructure.

Schmid et al. (April 6, 2020). LAMP-Seq: Population-Scale COVID-19 Diagnostics Using a Compressed Barcode Space. Preprint downloaded April 9 from https://doi.org/10.1101/2020.04.06.025635