Alliance for Pandemic Preparedness

April 15, 2020

COVID-19: A model correlating BCG vaccination to protection from mortality implicates trained immunity

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  • Green et al determine that BCG vaccination is correlated with protection from death from COVID-19. This correlation to new and existing studies and data suggest causal protective mechanisms that have been previously and rigorously demonstrated to be mediated by BCG vaccination. These mechanisms converge on “trained immunity,” suggesting that this may be an important mechanism in individuals demonstrating protection from the lethal effects of COVID-19.

Green et al. (April 15, 2020). COVID-19: A model correlating BCG vaccination to protection from mortality implicates trained immunity. Pre-print downloaded Apr 15 from https://www.medrxiv.org/content/10.1101/2020.04.10.20060905v1.full.pdf