Alliance for Pandemic Preparedness

April 21, 2020

Development and Multicenter Performance Evaluation of The First Fully Automated SARS-CoV-2 IgM and IgG Immunoassays

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  • Qian et al evaluated the clinical sensitivity of IgM and IgG SARS-CoV-2 antibody testing using 972 non-COVID-19 patients, 586 normal donors, and 503 RT-PCR-confirmed cases.  
  • IgM and IgG show clinical sensitivity of 85.88% and 96.62% respectively for confirmed SARS-Cov-2 infection with RT-PCR.  These assays may add great value to nucleic acid testing.

Qian et al. (April 21, 2020). Development and Multicenter Performance Evaluation of The First Fully Automated SARS-CoV-2 IgM and IgG Immunoassays. Pre-print downloaded Apr 21 from https://doi.org/10.1101/2020.04.16.20067231