April 21, 2020

Outcomes of hydroxychloroquine usage in United States veterans hospitalized with Covid-19

Category: Article Summary

Topic: Testing and Treatment

• This retrospective analysis of 368 patients who had received hydroxychloroquine (with azithromycin or alone) explored the association between treatment and the primary outcomes of mechanical ventilation and death.  
• No evidence was found of reduced risk of mechanical ventilation, and use of hydroxychloroquine alone was associated with an increased risk of overall mortality. These findings highlight the importance of randomized controlled study results before widespread adoption of these drugs. 

Magagnolia et al. (April 21, 2020). Outcomes of hydroxychloroquine usage in United States veterans hospitalized with Covid-19. Pre-print downloaded Apr 21 from https://doi.org/10.1101/2020.04.16.20065920