April 28, 2020

Long period dynamics of viral load and antibodies for SARS-CoV-2 infection: an observational cohort study

Category: Article Summary

Topic: Testing and Treatment

• This retrospective observational case series of 33 patients with SARS-CoV-2 pneumonia reviewed analysis of throat swabs, sputum, stool, and blood samples to evaluate viral load, IgM, IgG, spike protein receptor binding domain (RBD), and nucleocapsid.
• Results suggest that viral RNA persists in sputum and stool samples for a long time, and that anti-RBD may serve as a protective antibody against SARS-CoV-2 that is related to viral persistence and is valuable for development of vaccines. 

Huang et al. (April 27, 2020). Long period dynamics of viral load and antibodies for SARS-CoV-2 infection: an observational cohort study. Pre-print downloaded Apr 27 from https://doi.org/10.1101/2020.04.22.20071258