Alliance for Pandemic Preparedness

May 1, 2020

Second-Trimester Miscarriage in a Pregnant Woman With SARS-CoV-2 Infection

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  • Baud et al. present a single case report of a second trimester miscarriage in a pregnant woman with COVID-19. The authors found evidence that the miscarriage was related to placental infection with SARS-CoV-2. Findings from a placental histological examination and fetal autopsy found that the placental submembrane and cotyledon both tested positive for SARS-CoV-2, while amniotic fluid, maternal blood, and fetal samples were all SARS-CoV-2 negative.

Baud et al. (April 30, 2020). Second-Trimester Miscarriage in a Pregnant Woman With SARS-CoV-2 Infection. JAMA. https://doi.org/10.1001/jama.2020.7233