Alliance for Pandemic Preparedness

May 6, 2020

Effective Heat Inactivation of SARS-CoV-2

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  • Wang et al. evaluate the stability of SARS-CoV-2 under four different heat conditions (37, 42, 56, 60°C) and report that the virus is stable at 37°C for at least 24 hours. However, heating at 56°C for 30 minutes effectively inactivates the virus while preserving the stability of viral RNA for further analysis in both human sera and sputum samples. These findings provide a practical way to inactivate infectious virus in clinical specimens. 

Wang et al. (May 5, 2020). Effective Heat Inactivation of SARS-CoV-2. Medical Science Monitor.  https://doi.org/10.1101/2020.04.29.20085498