May 12, 2020

Development and External Validation of a Prognostic Tool for COVID-19 Critical Disease

Category: Article Summary

Topic: Clinical Characteristics and Health Care Setting

• Tools to predict COVID-19 severity will assist in management of critical care capacity and enable earlier targeted interventions to improve outcomes. These authors created a web-based tool for their prognostic model, which defined critical disease as ICU admission, ventilation, or death. They fit the model to patients presenting to UC Irvine, and validated on patients presenting to Emory Healthcare. Covariates included comorbidities, presenting vital signs, and laboratory values. Model discrimination in the validation cohort was found to be high (concordance statistic 0.94, 95% CI: 0.87, 1.01).   

Chow et al. (May 11, 2020). Development and External Validation of a Prognostic Tool for COVID-19 Critical Disease. Pre-print downloaded May 12 from https://doi.org/10.1101/2020.05.06.20093435