May 13, 2020

Treatment of COVID-19 Patients with Convalescent Plasma in Houston Texas

Category: Article Summary

Topic: Testing and Treatment

• Salazar et al. explored the safety of convalescent plasma therapy among 25 patients with severe and/or life-threatening COVID-19 disease enrolled at the Houston Methodist hospitals. Patients were transfused with convalescent plasma obtained from donors with confirmed SARS-CoV-2 infection who been symptom free for 14 days. 
• At 7 days post-transfusion, 9 patients had at least a 1-point improvement in clinical scale, and 7 of those were discharged. By 14 days, 19 (76%) patients had at least a 1-point improvement in clinical status and 11 were discharged. No adverse events due to plasma transfusion were observed.  

Salazar et al. (May 13, 2020). Treatment of COVID-19 Patients with Convalescent Plasma in Houston Texas. Pre-print downloaded May 13 from https://doi.org/10.1101/2020.05.08.20095471