Alliance for Pandemic Preparedness

May 15, 2020

Combination of Four Clinical Indicators Predicts the Severe/Critical Symptom of Patients Infected COVID-19

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  • Using data on all 336 cases of COVID-19 in Shanghai, China through March 12, as well as 220 clinical and laboratory records, Sun et al. built a risk prediction model for discriminating severe/critical illness. Thirty-six clinical indicators were found to be significantly associated with severe/critical symptoms. The AUC for the final model (Support Vector Machine) for discriminating severe/critical cases from mild cases was 0.98 in the test set.  

Sun et al. (May 13, 2020). Combination of Four Clinical Indicators Predicts the Severe/Critical Symptom of Patients Infected COVID-19. Journal of Clinical Virology. https://doi.org/10.1016/j.jcv.2020.104431