May 19, 2020

Distinct Systems Serology Features in Children Elderly and COVID Patients

Category: Article Summary

Topic: Clinical Characteristics and Health Care Setting

• Selva et al. investigated the cross-reactivity of SARS-CoV-2 and other circulating human coronavirus antibody responses in healthy children (n=89), adults (n=98), elderly (n=57), and COVID-19 patients (n=19). Their results suggest that less-experienced humoral immunity that is observed in children, associated with higher IgM, may have the potential to induce more potent antibodies upon SARS-CoV-2 infection, potentially making a future vaccine more effective among children.

Selva et al. (May 18,2020). Distinct Systems Serology Features in Children Elderly and COVID Patients. Pre-print downloaded May 19 from https://doi.org/10.1101/2020.05.11.20098459