Alliance for Pandemic Preparedness

May 27, 2020

COVID-19 Serology at Population Scale SARS-CoV-2-Specific Antibody Responses in Saliva

Category:

Topic:

  • [pre-print, not peer reviewed] Randad et al. evaluated the correlation of results obtained in 167 saliva samples vs. 324 serum samples and found that SARS-CoV-2 appears to trigger a humoral immune response resulting in the almost simultaneous rise of IgG, IgM and IgA levels in serum and in saliva, consistent with the stimulation of existing cross-reactive B cells. 
  • SARS-CoV-2 antibody testing in saliva may play a role in large-scale sero-surveillance for COVID-19. 

Randad et al. (May 26, 2020). COVID-19 Serology at Population Scale SARS-CoV-2-Specific Antibody Responses in Saliva. Pre-print downloaded May 27 from https://doi.org/10.1101/2020.05.24.20112300