June 3, 2020

Expression of Concern: Hydroxychloroquine or Chloroquine with or without a Macrolide for Treatment of COVID-19: A Multinational Registry Analysis

Category: Article Summary

Topic: Testing and Treatment

• The Lancet and the New England Journal of Medicine have both issued Expressions of Concern about the validity of the data used for two articles regarding the use of hydroxychloroquine or chloroquine for the treatment of COVID-19 published by authors associated with a company called Surgisphere Corporation. These articles both utilized retrospective data from an international database that included electronic health records from 169 hospitals on three continents. 

Editors. (June 3, 2020). Expression of Concern: Hydroxychloroquine or Chloroquine with or without a Macrolide for Treatment of COVID-19: A Multinational Registry Analysis. The Lancet. https://doi.org/10.1016/S0140-6736(20)31290-3  

Rubin. (June 2, 2020). Expression of Concern: Mehra MR et Al. Cardiovascular Disease, Drug Therapy, and Mortality in Covid-19. N Engl J Med. DOI: 10.1056/NEJMoa2007621. The New England Journal of Medicine. https://doi.org/10.1056/NEJMe2020822