Alliance for Pandemic Preparedness

June 8, 2020

Association Between Mode of Delivery Among Pregnant Women With COVID-19 and Maternal and Neonatal Outcomes in Spain

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  • Severe adverse maternal outcomes occurred in 9/82 (11%) pregnant women who tested positive for SARS-CoV-2 in a Spanish cohort. Four of the 9 had mild COVID-19 symptoms and 5/9 had severe symptoms.  
  • Women who delivered by cesarean sections (necessitated by COVID-19 symptoms in 100% of those with severe symptoms and 10% of those with mild symptoms) were more likely to require ICU admission and experience clinical deterioration than those with vaginal delivery and their newborns were more likely to be admitted to the NICU; however this study did not include mother-infant dyads undergoing cesarean section in the absence of maternal COVID-19 infection. Five infants eventually tested positive for SARS-CoV-2 and two developed COVID-19 symptoms, which resolved after 48 hours.  

Martínez-Perez et al. (June 8, 2020). Association Between Mode of Delivery Among Pregnant Women With COVID-19 and Maternal and Neonatal Outcomes in Spain. JAMA. https://doi.org/10.1001/jama.2020.10125