Alliance for Pandemic Preparedness

June 8, 2020

Detection of SARS-CoV-2 Antibodies Using Commercial Assays and Seroconversion Patterns in Hospitalized Patients

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  • Tuaillon et al. evaluated six point-of-care (POC) and three ELISA tests to determine their sensitivity and specificity for the detection of SARS-CoV-2 antibodies between 1 day and >15 days after onset of symptoms. Most tests detected antibodies in at least 50% of samples by day 7 and nearly all tests were positive for >80% of samples after 15 days, although none of the tests were positive for 100% of the samples. Three assays had a specificity of less than 90%. 

Tuaillon et al. (June 2020). Detection of SARS-CoV-2 Antibodies Using Commercial Assays and Seroconversion Patterns in Hospitalized Patients. The Journal of Infection. https://doi.org/10.1016/j.jinf.2020.05.077