Alliance for Pandemic Preparedness

June 12, 2020

Association of Asthma and Its Genetic Predisposition with the Risk of Severe COVID-19

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  • Individuals with asthma (n=65,677) in the UK Biobank had a significantly higher risk of severe COVID-19 (aOR=1.39; 95%CI 1.13-1.71), compared to those without asthma or COPD (n=427,091), after adjusting for confounders. The risk was even greater in those who also had COPD (aOR=1.82; 95%CI 1.16-2.86). On subgroup analysis, this effect was only seen in those with non-allergic asthma.  

Zhu et al. (June 6, 2020). Association of Asthma and Its Genetic Predisposition with the Risk of Severe COVID-19. The Journal of Allergy and Clinical Immunology. https://doi.org/10.1016/j.jaci.2020.06.001