June 12, 2020

Risk Factors for Disease Progression in Mild to Moderate COVID-19 Patients- a Multi-Center Observational Study

Category: Article Summary

Topic: Clinical Characteristics and Health Care Setting

• Cen et al. reported clinical outcomes and risk factors from 1,007 patients with mild to moderate COVID-19 in 3 hospitals in Wuhan, China. Over 4 weeks of follow-up, 22% progressed to severe disease, 2% progressed to critical disease, and 4% died. Increasing age, male sex, hypertension, chronic obstructive pulmonary disease, and coronary artery disease were all associated with higher likelihood of progression, while history of smoking was associated with lower risk of progression.  

Cen et al. (June 8, 2020). Risk Factors for Disease Progression in Mild to Moderate COVID-19 Patients- a Multi-Center Observational Study. Clinical Microbiology and Infection. https://doi.org/10.1016/j.cmi.2020.05.041