June 23, 2020

Outcomes among HIV-Positive Patients Hospitalized with COVID-19

Category: Article Summary

Topic: Clinical Characteristics and Health Care Setting

• A retrospective cohort study that matched 21 HIV-positive COVID-19 patients (median CD4 count 298/uL, <200/uL for 6 patients; all on HAART) to 42 HIV-negative COVID-19 patients hospitalized at New York University Langone Health found those with HIV co-infection had a non-significantly higher risk of changes on chest CT (91% vs 64%), ICU admission (29% vs 17%), mechanical ventilation (24% vs 12%), death or transfer to hospice (29% vs 24%), and peak values for most inflammatory markers. There was no difference in frequency of thrombotic events or myocardial infarction. 

Karmen-Tuohy et al. (June 2020). Outcomes among HIV-Positive Patients Hospitalized with COVID-19. Journal of Acquired Immune Deficiency Syndromes (2020). https://doi.org/10.1097/QAI.0000000000002423