Alliance for Pandemic Preparedness

June 29, 2020

Seroprevalence of Antibodies to SARS-CoV-2 in Six Sites in the United States March 23-May 3 2020

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  • [pre-print, not peer-reviewed] Havers et al. report findings from a large seroprevalence study using a convenience sample of serum collected for routine clinical purposes from patients in Connecticut (CT), south Florida (FL), Missouri (MO), New York City metro region (NY), Utah (UT), and the Puget Sound region (WA) from March 23-May 3.  
  • Out of a total of almost 12,000 samples, seroprevalence was lowest in WA at 1.13% (95% CI 0.70%, 1.94%), and highest in NY at 6.93% (95% CI 5.02%, 8.92%). 
  • Based on these results, the estimated number of total infections per confirmed infection ranged from 6 to 24 across these sites. [EDITORIAL NOTE: Individuals undergoing routine clinical testing may not be representative of the seroprevalence in the general population of these sites] 

Havers et al. (June 26, 2020). Seroprevalence of Antibodies to SARS-CoV-2 in Six Sites in the United States March 23-May 3 2020. Pre-print downloaded June 26 from https://doi.org/10.1101/2020.06.25.20140384