July 2, 2020

Risk Factors Associated with COVID-19 Infection: A Retrospective Cohort Study Based on Contacts Tracing

Category: Article Summary

Topic: Clinical Characteristics and Health Care Setting

• In a retrospective cohort study of 11,580 contacts of COVID-19 cases in Guangdong, China the overall risk of SARS-CoV2-infection based on RT-PCR testing was 4.5% (515/11,580). Higher risk was seen among children (RR=2.6) and old people aged 60-69 years (RR=5.3) compared to young adults aged 20-29 years, higher among females than males (RR=1.66), and higher among family members of an index cases (spouse: RR=20.7; non-spouse family members: RR=9.6). Infection risk was higher for contacts exposed to an index case during the symptomatic period (RR=2.2) or to an index case with critically severe symptoms (RR=1.6). 

Liu et al. (July 1, 2020). Risk Factors Associated with COVID-19 Infection: A Retrospective Cohort Study Based on Contacts Tracing. Emerging Microbes & Infections. https://doi.org/10.1080/22221751.2020.1787799