Alliance for Pandemic Preparedness

July 7, 2020

Clinical Validity of Serum Antibodies to SARS-CoV-2



  • Caturegli et al. evaluate test characteristics of a serum antibody test for SARS-COV-2 in a case-control study among hospitalized patients with confirmed COVID-19 (n=60) and controls from healthy lab employees and patients hospitalized for reasons other than COVID-19 (n=513)Sensitivity for detection of SARS-CoV-2 IgG was 97.6% and specificity was 98.8% when performed at least 14 days after symptom onset.   

Caturegli et al. (July 6, 2020). Clinical Validity of Serum Antibodies to SARS-CoV-2. Annals of Internal Medicine.