July 7, 2020

Clinical Validity of Serum Antibodies to SARS-CoV-2

Category: Article Summary

Topic: Testing and Treatment

• Caturegli et al. evaluate test characteristics of a serum antibody test for SARS-COV-2 in a case-control study among hospitalized patients with confirmed COVID-19 (n=60) and controls from healthy lab employees and patients hospitalized for reasons other than COVID-19 (n=513). Sensitivity for detection of SARS-CoV-2 IgG was 97.6% and specificity was 98.8% when performed at least 14 days after symptom onset.   

Caturegli et al. (July 6, 2020). Clinical Validity of Serum Antibodies to SARS-CoV-2. Annals of Internal Medicine. https://pubmed.ncbi.nlm.nih.gov/32628534/