July 10, 2020

Pathophysiology, Transmission, Diagnosis, and Treatment of Coronavirus Disease 2019 (COVID-19)

Category: Article Summary

Topic: Testing and Treatment

• A review article summarizes the current state of knowledge about SARS-CoV-2 and COVID-19 and highlights gaps in knowledge about transmission, infection, and treatment. Dexamethasone shows promise in reducing 28-day mortality, while convalescent plasma has not yet been shown to not shorten time to recovery. At least 120 SARS-CoV-2 vaccines are under development. Until an effective vaccine is developed, face masks, physical distancing, and contact tracing remain the primary methods to reduce spread.  

Wiersinga et al. (July 10, 2020). Pathophysiology, Transmission, Diagnosis, and Treatment of Coronavirus Disease 2019 (COVID-19). JAMA. https://doi.org/10.1001/jama.2020.12839